Publications by authors named "Jiye Lin"
Regulatory T (Treg) cells are thought to contribute to tumor pathogenesis by suppressing tumor immunosurveillance and antitumor immunity. T follicular regulatory (Tfr) cells are a recently characterized Treg subset that expresses both the Treg transcription factor (TF) Foxp3 and the T follicular helper (Tfh) TF Bcl-6. The role of Tfr cells in glioma patients remains unclear.
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- Human WBSCR22 is linked to poor outcomes in glioma patients and is found to be highly abundant in glioma cell lines.
- Disrupting WBSCR22 leads to reduced growth, invasion, and migration of glioma cells, while increased expression of WBSCR22 has the opposite effect.
- The study suggests that WBSCR22 functions by regulating specific proteins and is directly targeted by miR-146b-5p, highlighting its potential as a therapeutic target in glioma treatment.
Objective: Using three-dimensional (3D) printing to create individualized patient models of the skull base, the optic chiasm and facial nerve can be previsualized to help identify and protect these structures during tumor removal surgery.
Methods: Preoperative imaging data for 2 cases of sellar tumor and 1 case of acoustic neuroma were obtained. Based on these data, the cranial nerves were visualized using 3D T1-weighted turbo field echo sequence and diffusion tensor imaging-based fiber tracking.