Publications by authors named "Jiwon Jung"
PAX2-related disorders encompass renal coloboma syndrome (RCS) and hereditary focal segmental glomerulosclerosis (FSGS) type 7. We retrospectively analyzed 27 Korean patients with PAX2 pathogenic variants detected between 2004 and 2022 and conducted a literature review of 328 cases, including 301 previously reported. In our cohort, 19 had RCS, 4 had FSGS, and 4 had isolated congenital anomalies of the kidneys and urinary tract.
View Article and Find Full Text PDFBackground/aims: Krebs von den Lungen-6 (KL-6) is associated with prognosis in patients with COVID-19. However, there is limited data on the correlation between the prognosis of COVID-19 and varying KL-6 levels at different time points. We investigated the optimal cutoff values of the initial and peak serum KL-6 levels to predict mortality and evaluated their correlation with mortality.
View Article and Find Full Text PDFBackground: Tigecycline is widely used to treat a variety of bacterial infections despite concerns regarding increased mortality in severe infections. Previous case reports have documented breakthrough bloodstream infections (BSI) during tigecycline therapy. This study aimed to investigate the incidence of, and risk factors for, breakthrough BSI during tigecycline monotherapy.
View Article and Find Full Text PDFBackground: The rising number of cancer survivors and the shortage of health care professionals challenge the accessibility of cancer care. Health technologies are necessary for sustaining optimal patient journeys. To understand individuals' daily lives during their patient journey, qualitative studies are crucial.
View Article and Find Full Text PDFBackground: In 2023, we experienced an outbreak from a case of undiagnosed crusted scabies, resulting in a significant number of exposed individuals and secondary cases. In this report, we describe the outbreak control measures, the attack rate, and the risk factors for acquisition of scabies among healthcare workers (HCWs).
Methods: This study was conducted in a 2,700-bed tertiary care hospital in Seoul, South Korea.
Background: Identifying risk factors for mortality in patients with bacteremia (SAB) is crucial due to its high fatality. However, data on risk factors for infection-attributable deaths considering competing risk events such as non-infection-attributable deaths remain limited. We performed a competing risk analysis to elucidate risk factors associated with 30-day infection-attributable mortality in a large cohort of patients with SAB.
View Article and Find Full Text PDFBackground: Although recommended isolation periods for Coronavirus disease 2019 (COVID-19) have been shortened as the pandemic has subsided, prolonged Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) shedding remains common in immunocompromised patients. This study estimated the probability of viral clearance in these patients based on elapsed days and specific risk factors.
Methods: We prospectively enrolled immunocompromised patients with a confirmed COVID-19 diagnosis from January 2022 to May 2023 during the Omicron variant era.
Article Synopsis
- Fascioliasis is a disease mainly found in livestock but has seen an increase in human cases in Korea, linked to a green vegetable juice delivery service.
- Patients diagnosed with fascioliasis often presented with specific symptoms like eosinophilia and were treated with triclabendazole, showing varying recovery patterns in liver abscesses over time.
- MRI findings indicated that late-diagnosed patients had a higher incidence of bile duct issues, while antibody levels and eosinophil counts significantly declined after treatment, suggesting the need for ongoing monitoring.
Objectives: To investigate the associations between gadolinium-based contrast agent (GBCA) administration and the occurrence of acute kidney injury (AKI) in pediatric patients, and to determine the risks associated with AKI.
Materials And Methods: This retrospective study was conducted on pediatric patients who underwent contrast-enhanced or unenhanced MRI between January 1st, 2015, and June 30th, 2021. Examinations were included if they had data on height and serum creatinine levels within 3 months before and 2 days after the examinations.
The morphology, morphogenesis, molecular phylogeny, and the resting cyst morphology of the freshwater ciliate, Crassohymena primicirrata (Berger and Foissner, 1987) n. gen., n.
View Article and Find Full Text PDFOral vancomycin use and incidence of vancomycin-resistant enterococci: time-series analysis.
Antimicrob Resist Infect Control
December 2024
Article Synopsis
- Vancomycin exposure is linked to an increased risk of colonization by vancomycin-resistant enterococci (VRE), particularly through oral administration, which was examined in this retrospective study.
- The study analyzed data from a large hospital in South Korea over a ten-year period and found a significant correlation between oral vancomycin use and the incidence of hospital-acquired VRE.
- The findings underscore the importance of implementing antibiotic stewardship strategies to manage oral vancomycin use and prevent the spread of VRE in healthcare settings.
Article Synopsis
- The study examines how immunity to COVID-19 has evolved from the pandemic to endemic phases, focusing on the updated XBB.1.5 monovalent vaccine (MonoV).
- Researchers tracked 327 healthcare workers over three years, assessing various immunity responses through blood samples collected at different times.
- Findings reveal that while antibody levels declined initially, they were maintained and even enhanced in the endemic phase, with the MonoV showing significantly improved neutralization against new virus strains compared to previous vaccines.
Background: Hypertension is one of the most important complications of chronic kidney disease (CKD) as it exacerbates disease progression in children. The aim of this study is to identify characteristics and factors associated with hypertension in children with CKD.
Methods: This is a cross-sectional study using baseline data from the 10-year ongoing cohort study named KNOW-PedCKD (Korean Cohort Study for Outcome in Patients with Pediatric Chronic Kidney Disease).
Article Synopsis
- ST72 is a common strain of methicillin-resistant Staphylococcus aureus (MRSA) in Korea, and there's a growing need to study its methicillin-susceptible variant (MSSA) due to rising infections.
- This study reviewed cases from a hospital over 11 years, finding that 35.5% of patients with ST72 had MSSA infections, which were less likely to show multidrug resistance compared to MRSA.
- Both MSSA and MRSA had similar clinical characteristics, but MSSA showed a lower recurrence rate after 90 days while mortality rates were comparable, highlighting an alarming trend of MSSA increase in hospital settings.
Article Synopsis
- This text serves as a correction to a previously published article found on page e237 in volume 39.
- The specific PMID for the original article is 39252682.
- The correction addresses specific errors or clarifications related to the content of that article.
Guiding endogenous regeneration of bone defects using biomaterials and regenerative medicine is considered an optimal strategy. One of the effective therapeutic approaches involves using transgene-expressed stem cells to treat tissue destruction and replace damaged parts. Among the various gene editing techniques for cells, clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) is considered as a promising method owing to the increasing therapeutic potential of cells by targeting specific sites.
View Article and Find Full Text PDFBackground: The pathophysiological mechanisms underlying the post-acute sequelae of severe acute respiratory syndrome coronavirus 2 infection (PASC) are not well understood. Our study aimed to investigate various aspects of theses mechanisms, including viral persistence, immunological responses, and laboratory parameters in patients with and without PASC.
Methods: We prospectively enrolled adults aged ≥ 18 years diagnosed with coronavirus disease 2019 (COVID-19) between August 2022 and July 2023.
As atomic-scale etching and deposition processes become necessary for manufacturing logic and memory devices at the sub-5 nm node, the limitations of conventional plasma technology are becoming evident. For atomic-scale processes, precise critical dimension control at the sub-1 nm scale without plasma-induced damage and high selectivity between layers are required. In this paper, a plasma with very low electron temperature is applied for damage-free processing on the atomic scale.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on investigating the occurrence of aspergillosis coinfection in patients diagnosed with mucormycosis, as information on this topic is limited, especially regarding antifungal treatment optimization.
- Researchers reviewed medical records of 67 adult patients who had been diagnosed with mucormycosis from 2007 to 2023, using a combination of fungal cultures and PCR assays to identify the presence of Aspergillus species.
- The findings revealed that about 31% of the patients had evidence of aspergillosis coinfection, with higher positive rates of specific diagnostic markers in this group compared to those with only mucormycosis, indicating a need for more detailed future research on co-infections for improved treatment
The seropositivity of measles antibodies among 261 autologous stem cell transplant recipients (ASCTs) in Korea, assessed approximately 1-2 years after transplant (median, 11 months; interquartile range, 9-14), was significantly lower than age- and sex-matched control healthcare workers (83.1% [217/261] vs. 90.
View Article and Find Full Text PDFThis study evaluated the determinants of mortality and the T cell immune response in patients with persistent Staphylococcus aureus bacteremia (SAB). This was a prospective cohort study and patients with confirmed SAB were enrolled from 2008 to 2020. We compared clinical, microbiological, and genotypic features between surviving and deceased patients with persistent SAB.
View Article and Find Full Text PDFBackground: We aimed to evaluate the performance of ceiling-mounted UV-C lamps.
Methods: This study was conducted in an empty room with UV-C lamps in the biocontainment unit of a tertiary care hospital in South Korea. Each pathogen (Staphylococcus aureus, Escherichia coli, Candida krusei, Bacillus cereus, and Mycobacterium peregrinum) was inoculated on blood agar plates and placed in 20 selected places from the UV-C lamp, and irradiation was applied for 15 min.
Article Synopsis
- The study looked at patients with a serious infection called hVISA who were treated with a medicine called vancomycin and found that a lot of them (78%) didn't get better.
- Older patients and those with serious health problems had a harder time improving compared to younger and healthier patients.
- Researchers discovered that age and how severe the infection was played big roles in whether the treatment worked or not, suggesting doctors should pay extra attention to these factors when treating hVISA infections.