Objective: This meta-analysis aims to evaluate the impact of these two techniques on postoperative pain and quality of life in early-stage NSCLC patients.
Methods: A comprehensive literature search was conducted in PubMed, Cochrane Library, Web of Science, and CNKI databases. Randomized controlled trials and cohort studies comparing single-port and three-port VATS lobectomy for early-stage NSCLC were included.
Although silver nanoparticles (AgNPs) have the effective antibacterial property, its application was limited by the accumulated toxicity. It was necessary to develop a carrier material to immobilize AgNPs. In this study, for the first time, thiol-modified carbon spheres (TMCS) were synthesized by hydrothermal method, which was used to immobilize AgNPs.
View Article and Find Full Text PDFConventional light-driven antimicrobial strategies of zinc oxide (ZnO) are limited by inadequate illumination in dark environments. In this study, carboxylated cellulose nanocrystals (MCNC) mediated flower-like ZnO (C@Z) with self-promoted reactive oxygen species release under dark is fabricated. The adsorption of Zn ions on MCNC prompts the growth of ZnO along the (002) crystal plane, forming a flower-like hybrid with superior dispersibility and oxygen vacancies compared to MCNC-free ZnO, which exposes the (100) plane.
View Article and Find Full Text PDFBackground: The therapeutic strategy for patients with spontaneous rupture of the esophagus includes surgical repair, endoscopic therapy, supportive care, and others. However, no evidence exists to direct clinical decision-making regarding the choice of operative and nonoperative management. This study aimed to determine the clinical efficacy of different therapeutic strategies in both general and stratified patients.
View Article and Find Full Text PDFNumerous studies reported the concentration of agonists of aryl hydrocarbon receptor (AhR) in indoor dust by target chemical analysis or the biological effects of activating the AhR by indoor extracts, but the major AhR agonists identification in indoor dust were rarely researched. In the present study, the indoor dust samples were collected for 7-ethoxyresorufin O-deethylase (EROD) assay and both non-targeted and targeted chemical analysis for AhR agonists by gas chromatography quadrupole time-of-flight mass spectrometry and gas chromatography-mass spectrometry analysis. Coupled with non-targeted analysis and toxicity Forecaster (ToxCast)/Tox21 database, 104 ToxCast chemicals were screened to be able to induce EROD response.
View Article and Find Full Text PDFCRC is a common malignant tumor in the gastrointestinal tract, and its incidence has increased significantly in recent years. Several studies revealed that lipid metabolism reprogramming contributed to tumorigenicity and malignancy by interfering with energy production, membrane formation, and signal transduction in cancers. ATGL is a kind of hydroxy fatty acid ester of fatty acid synthase, and its role in tumor remains controversial.
View Article and Find Full Text PDFSeveral studies have evaluated the human exposure of phthalate esters (PAEs) in PM via inhalation route, however, inhalation bioaccessibility and the lung cell penetration of PAEs were barely considered in risk assessment. In the present study, PM samples collected from indoor environments were investigated for inhalation bioaccessibility of PAEs using two simulated lung fluids (gamble's solution (GMB) and artificial lysosomal fluid (ALF)). The results showed that the inhalation bioaccessibility of PAEs (except for diethyl phthalate) under healthy state (GMB: 8.
View Article and Find Full Text PDFFor the high-valued utilization of hemicelluloses and for realizing the controllable synthesis of NPs, this paper's aim is to combine xylan, chitosan and nanometal materials at the same time. In this research study, firstly, propargyl xylan was synthesized via nucleophilic substitution reaction between xylan and propargyl bromide in NaOH solution. On the other hand, a tosyl group was introduced onto the 6th position of synthesized quaternized chitosan (QCS), and the azide group replaced the tosyl group to obtain 6-amido-QCS (QCS-N).
View Article and Find Full Text PDFThe persistence of antibiotics in sewage treatment plants in recent years has become a serious problem. Meanwhile, humic acid and ammonia nitrogen are widely distributed in natural reservoirs and might influence the sorption, migration and transformation of antibiotics. In this study, natural zeolite (NZ) was evaluated as an adsorbent for the removal of levofloxacin (LEV).
View Article and Find Full Text PDFAiming at the ecological footprint model, the traditional trade adjustment method only considered the international trade process at the urban scale, ignoring the trade footprint generated by domestic trade and indirect trade in various products. This paper adopts the urban-scale ecological footprint model based on the macro-trade adjustment method to calculate the trade adjustment coefficient of biological products and the energy trade adjustment coefficient respectively to correct the trade footprint. The results showed that the per capita ecological deficit showed a straight upward trend, from 0.
View Article and Find Full Text PDFThe rapid development of consumer electronics, artificial intelligence, and clinical medicine generates an increasing demand for flexible pressure sensors, whose performance depends significantly on sensitive materials with high flexibility and proper conductivity. MXene, a type of 2D nanomaterial, has attracted extensive attention due to its good electrical conductivity, hydrophilicity, and flexibility. The synthesis methods for MXenes make it relatively easy to control their microstructure and surface termination groups.
View Article and Find Full Text PDFOur previous studies have shown that inoculation of the oral cavity of "humanized" B6.DR1/4 mice with the periodontal pathogen Porphyromonas gingivalis results in an increase in the percentage of circulating Th17 cells, loss of bone and an exacerbation of experimental autoimmune arthritis. The aim of this study was to assess the role played by the human HLA-DRβ molecule containing the shared epitope supplied as a transgene to I-A˚ (murine class II null) C57BL/6 (B6) mice in driving these findings.
View Article and Find Full Text PDFInhalation bioaccessibility of polycyclic aromatic hydrocarbons (PAHs) in PM was assessed in numerous studies, however, the lung cell uptake and penetration of PAHs was seldom taken into account in risk assessment. In the present study, eighteen indoor PM samples collected from Guangzhou, China were analyzed for the inhalation bioavailability of PAHs combining the inhalation bioaccessibility and cell absorption of PAHs. Two simulated epithelial lung fluid mimicking the healthy condition (as represented by gamble's solution (GMB), pH = 7.
View Article and Find Full Text PDFFront Bioeng Biotechnol
November 2020
At present, there are various wound dressings that can protect the wound from further injury or isolate the external environment in wound treatment. Whereas, infection and slow self-healing still exist in wound healing process. Therefore, it is urgent to develop an ideal wound dressing with good biocompatibility and strong antibacterial activity to promote wound healing.
View Article and Find Full Text PDFJ Environ Sci Health A Tox Hazard Subst Environ Eng
January 2021
Brominated flame retardants (BFRs) in house dust have raised significant concern around the world. However, few studies have reported the correlation between BFR concentrations in house dust and children's hair samples. In this study, BFR concentrations in house dust and children's hair were measured.
View Article and Find Full Text PDFChitosan (CS) can be used for the preparation of carbon materials with different morphologies due to its excellent properties, but there are no reports on its spherical morphology. In this study, a feasible step-by-step strategy was proposed to fabricate nitrogen-containing chitosan-based porous carbon microspheres (CPCM) in HCl and KOH. The unique spherical morphology and honeycomb-like porous structure of CPCM were accurately regulated.
View Article and Find Full Text PDFNumerous studies focused on the human exposure to plasticizers via dermal contact; however, the percutaneous penetration of plasticizers was seldom considered in exposure assessment. In the present study, skin wipes of palms, back-of-hands, and forehead were collected from 114 participants (ages: 18-27). There was no significant difference between the levels of phthalates from palms and back-of-hand, while all phthalates collected from the forehead were significantly higher than those from palms and back-of-hand ( < 0.
View Article and Find Full Text PDFThe transcriptomic response of green microalga Chlorella sorokiniana exposure to environmentally relevant concentration of cadmium(II) (Cd) and 4-n-nonylphenol (4-n-NP) was compared in the present study. Cd and 4-n-NP exposure showed a similar pattern of dys-regulated pathways. The photosystem was affected due to suppression of chlorophyll biosynthesis via down-regulation of Mg-protoporphyrin IX chelatase subunit ChlD (CHLD) and divinyl chlorophyllide a 8-vinyl-reductase (DVR) in Cd group and via down-regulation of DVR in 4-n-NP group.
View Article and Find Full Text PDFAs a kind of potential absorbent, polysaccharide materials are limited due to weak stability, low absorption and recovery rate. Herein, a novel composite adsorbent - the magnetic composite gel beads (CMC/SA/graphene oxide@FeO) were prepared by combining carboxymethyl chitosan (CMC), sodium alginate (SA) with graphene oxide@FeO, and then utilized for the adsorption of Cu, Cd and Pb from the wastewater. The physicochemical property of CMC/SA/graphene oxide@FeO beads were characterized in detail.
View Article and Find Full Text PDFBiochem Biophys Res Commun
June 2019
Long non-coding RNA (lncRNAs), which are increasingly identified to be dysregulated in cancers, has been verified to participate in tumorigenesis and cancer development. LncRNA TTN-AS1 has been validated as an oncogene in several cancers, such as esophageal squamous cell carcinoma and cervical cancer. Here, we studied the role of TTN-AS1 in lung adenocarcinoma (LAD).
View Article and Find Full Text PDFSeveral studies indicate that human exposure to plasticizers via dermal pathway is not negligible, but the dermal bioaccessibility of phthalates and alternative plasticizers from the important environmental matrix including indoor dust and clothing and the importance weight of dermal exposure to those pollutants have been poorly studied. An in vitro physiologically based extraction test was employed to investigate the dermal bioaccessibility of target phthalates and alternative plasticizers from indoor dust and clothing. Temperature, incubation time, sweat/sebum ratio and solid/liquid ratio were selected to study their effects on the bioaccessibility.
View Article and Find Full Text PDFNowadays, traditional packaging films with weak activity or single function cannot satisfy the active packaging requirements. In this paper, novel multifunctional films (TNC/GSE/AgNPs) based on TEMPO-oxidized nano-cellulose (TNC), grape seed extract (GSE) and TNC immobilized silver nanoparticles (TNC@AgNPs) are reported. The results showed that transparent TNC/GSE/AgNPs films exhibited better mechanical properties, lower water vapor permeability and oxygen permeability compared to pure TNC films.
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