Preparation of a colorimetric hydrogel indicator reinforced with modified aramid nanofiber employing natural anthocyanin to monitor shrimp freshness.

The pH-responsive hydrogels have potential applications in food visualization detection, but their fragile mechanical properties limit their applicability. The excellent mechanical properties and thermal stability of aramid nanofibers (ANFs) can improve the structural stability of hydrogels. In this study, the surface properties of ANFs were enhanced through modification to improve their surface activity.

Numerical simulation study on opening blood-brain barrier by ultrasonic cavitation.

Experimental studies have shown that ultrasonic cavitation can reversibly open the blood-brain barrier (BBB) to assist drug delivery. Nevertheless, the majority of the present study focused on experimental aspects of BBB opening. In this study, we developed a three-bubble-liquid-solid model to investigate the dynamic behavior of multiple bubbles within the blood vessels, and elucidate the physical mechanism of drug molecules through endothelial cells under ultrasonic cavitation excitation.

PaMYB11 promotes suberin deposition in Norway spruce embryogenic tissue during cryopreservation: A novel resistance mechanism against osmosis.

The osmotic resistance mechanism has been extensively studied in whole plants or plant tissues. However, little is known about it in embryogenic tissue (ET) which is widely used in plant-based biotechnological systems. Suberin, a cell wall aliphatic and aromatic heteropolymer, plays a critical role in plant cells against osmosis stress.

Enhanced reduction of Cd uptake by wheat plants using iron and manganese oxides combined with citrate in Cd-contaminated weakly alkaline arable soils.

Iron (Fe) and manganese (Mn) oxides can be used to remediate Cd-polluted soils due to their excellent performance in heavy metal adsorption. However, their remediation capability is rather limited, and a higher content of available Mn and Fe in soils can reduce Cd accumulation in wheat plants due to the competitive absorption effect. In this study, goethite and cryptomelane were first respectively used to immobilize Cd in Cd-polluted weakly alkaline soils, and sodium citrate was then added to increase the content of available Mn and Fe content for further reduction of wheat Cd absorption.

Facile Construction of Chestnut-Like Structural Fireproof PDMS/Mxene@BN for Advanced Thermal Management and Electromagnetic Shielding Applications.

Composite polymer materials featured superior thermal conductivity, flame retardancy, and electromagnetic shielding performance are increasingly in demand due to the rapid development of highly miniaturized, portable, and flexible electronic devices. Herein, a facile and green ball milling shear method is utilized for generating MXene@Boron nitride (MXene@BN). The multi-functional fillers (MXene@BN) are constructed and incorporated into polydimethylsiloxane (PDMS) to prepare a multifunctional composite (PDMS/MXene@BN) for achieving improved electromagnetic interference (EMI) shielding performance and thermal conductivity as well as flame retardancy simultaneously.

Haemodynamic Effects on the Development and Stability of Atherosclerotic Plaques in Arterial Blood Vessel.

Studying the formation and stability of atherosclerotic plaques in the hemodynamic field is essential for understanding the growth mechanism and preventive treatment of atherosclerotic plaques. In this paper, based on a multiplayer porous wall model, we established a two-way fluid-solid interaction with time-varying inlet flow. The lipid-rich necrotic core (LRNC) and stress in atherosclerotic plaque were described for analyzing the stability of atherosclerotic plaques during the plaque growth by solving advection-diffusion-reaction equations with finite-element method.

Transcriptome-wide m6A methylation in natural yellow leaf of .

N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNA, and involved in various biological processes in plants. However, the distribution features and functions of mRNA m6A methylation have been poorly explored in woody perennial plants. In this study, a new natural variety with yellow-green leaves, named Maiyuanjinqiu, was screened from the seedlings of .

Analysis of polycomb repressive complex 2 (PRC2) subunits in Picea abies with a focus on embryo development.

Background: Conserved polycomb repressive complex 2 (PRC2) mediates H3K27me3 to direct transcriptional repression and has a key role in cell fate determination and cell differentiation in both animals and plants. PRC2 subunits have undergone independent multiplication and functional divergence in higher plants. However, relevant information is still absent in gymnosperms.

A novel carboxyl polymer-modified upconversion luminescent nanoprobe for detection of prostate-specific antigen in the clinical gray zonebase by flow immunoassay strip.

Prostate specific antigen (PSA) is a widely-used biomarker for the diagnosis, screening, and prognosis of prostate cancer (PCa). It is critical to develop a rapid and convenient method to accurately detect PSA levels, especially when the PSA levels are in the clinical gray area of 4-10 ng/mL. We developed a novel upconversion nanoparticle (UCNP)-based fluorescence lateral flow test strip for qualitatively and quantitatively detecting PSA.

Genome-wide identification of DnaJ gene family in and functional analysis of in leaf color formation.

DnaJs are the common molecular chaperone proteins with strong structural and functional diversity. In recent years, only several DnaJ family members have been found to be able to regulate leaf color, and it remains to be explored whether there are other potential members that also regulate this character. Here, we identified 88 putative DnaJ proteins from , and classified them into four types according to their domain.

Synthesis and Properties of a Novel Thermally Conductive Pressure-Sensitive Adhesive with UV-Responsive Peelability.

Thermally conductive pressure-sensitive adhesive (PSA) has received a great amount of attention in recent years, but the traditional PSA hardly loses adhesion properties after UV irradiation or heating. Therefore, endowing thermally conductive adhesive with UV-responsive peelability becomes a design strategy. Herein, vinyl-functionalized graphene (AA-GMA-G) is prepared by modifying graphene with acrylic acid and subsequently reacting with glycidyl methacrylate.

Mini review: Application of the somatic embryogenesis technique in conifer species.

The somatic embryogenesis (SE) process is better suited to large-scale production and automation than other clonal propagation methods such as the rooting of cuttings. SE is becoming a key technique to promote the asexual industrialization of conifers. Furthermore, somatic embryos are an ideal material to study the molecular mechanism of conifer embryo development, as the processes of somatic and zygotic embryo development are very similar.

An Ultra-Stretchable Polyvinyl Alcohol Hydrogel Based on Tannic Acid Modified Aramid Nanofibers for Use as a Strain Sensor.

The mechanical performance is critical for hydrogels that are used as strain sensors. -Aramid nanofiber (ANF) is preferable as an additive to the reinforce the mechanical performance of a poly(vinyl alcohol) (PVA). However, due to the limited hydrogen bond sites, the preparation of ultra-stretchable, ANF-based hydrogel strain sensor is still a challenge.

, and associates with increased fecal metabolites -4-Hydroxy-L-proline and Genistein in active pulmonary tuberculosis patients during anti-tuberculosis chemotherapy with isoniazid-rifampin-pyrazinamide-ethambutol (HRZE).

Purpose: To investigated the changes of gut microbiome and fecal metabolome during anti-tuberculosis chemotherapy with isoniazid (H)-rifampin (R)-pyrazinamide (Z)-ethambutol (E).

Patients And Methods: (1) In this study, we recruited 168 stool specimens from 49 healthy volunteers without (Mtb), 30 healthy volunteers with latently infected by Mtb, 41 patients with active tuberculosis (ATB), 28 patients with 2-month HRZE treatment and 20 patients with 2-month HRZE followed by 4-month HR treatment. (2) We used 16S rRNA sequencing and an untargeted Liquid Chromatograph Mass Spectrometer-based metabolomics to investigate the changes of gut microbiome and the alteration of fecal metabolome, respectively, during anti-TB chemotherapy.

Prediction of vascular injury by cavitation microbubbles in a focused ultrasound field.

Many studies have shown that microbubble cavitation is one mechanism for vascular injury under ultrasonic excitation. Previous work has attributed vascular damage to vessel expansions and invaginations due to the expansion and contraction of microbubbles. However, the mechanisms of vascular damage are not fully understood.

Integrated Lipidomic and Transcriptomic Analysis Reveals Phospholipid Changes in Somatic Embryos of in Response to Partial Desiccation.

Partial desiccation treatment (PDT) is an effective technology for promoting the germination and conversion of conifer somatic embryos (SEs). PDT, as a drought stress, induces intensive physiological responses in phospholipid metabolism, which are not well understood in the conifer SEs. Here, we integrated lipidomics, transcriptomics and proteomics analyses to reveal the molecular basis of lipid remodeling under PDT in SEs.

Improved diagnosis of type-1 diabetes mellitus using multiplexed autoantibodies ELISA array.

Autoantibodies are currently the most robust biomarkers of type 1 diabetes. However, single autoantibody targeted detection is still limited in diabetes diagnosis with poor performance. Here, we develop a multiplexed Array-ELISA assay that can detect five diabetes-related autoantibodies including glutamic acid decarboxylase antibody (GADA), insulinoma antigen 2 antibody (IA-2A), islet cell antibody (ICA), zinc transporter 8 autoantibody (ZnT8-A) and insulin antibody (IAA) simultaneously.

Dynamic observation of SARS-CoV-2 IgM, IgG, and neutralizing antibodies in the development of population immunity through COVID-19 vaccination.

Background: Currently, mass vaccine inoculation against coronavirus disease-2019 (COVID-19) has been being implemented globally. Rapid and the large-scale detection of serum neutralizing antibodies (NAbs) laid a foundation for assessing the immune response against SARS-CoV-2 infection and vaccine. Additional assessments include the duration of antibodies and the optimal time for a heightened immune response.

Terraced and 3D Pyramid-Shaped Polymer Single Crystal via Low Temperature-Assisted Microfluidic Technology.

3D pyramidal polymer single crystals provide spatial gradient variations within the crystal molecules, and these variations facilitate the study of the relationship between structure and properties within the molecules of various complexes with anisotropic structures. As described herein, a low-temperature-assisted microfluidic pore channeling approach is proposed to prepare structurally ordered polymer single crystals. A mixture of dichloromethane and dimethyl sulfoxide is used as a prepolymer, and a liquid microfluidic technique is employed to grow the end-functionalized polymers into 3D polymer single crystals.

Numerical analysis of the biomechanical effects on micro-vessels by ultrasound-driven cavitation.

Purpose: The goal of this study was to evaluate the biomechanical effects such as sonoporation or permeability, produced by ultrasound- driven microbubbles (UDM) within microvessels with various parameters.

Methods: In this study, a bubble-fluid-solid coupling system was established through combination of finite element method. The stress, strain and permeability of the vessel wall were theoretically simulated for different ultrasound frequencies, vessel radius and vessel thickness.

Tailorable Membrane-Penetrating Nanoplatform for Highly Efficient Organelle-Specific Localization.

Given the breadth of currently arising opportunities and concerns associated with nanoparticles for biomedical imaging, various types of nanoparticles have been widely exploited, especially for cellular/subcellular level probing. However, most currently reported nanoparticles either have inefficient delivery into cells or lack specificity for intracellular destinations. The absence of well-defined nanoplatforms remains a critical challenge hindering practical nano-based bio-imaging.

Numerical evaluation of high-intensity focused ultrasound- induced thermal lesions in atherosclerotic plaques.

The aim of this study is to estimate the effects of some acoustic parameters on thermal lesions of atherosclerotic plaques in high-intensity focused ultrasound (HIFU) fields. A fluid-solid thermal coupling model is presented for describing the temperature elevation and thermal ablation of atherosclerotic plaque. A finite element approach is used to solve the coupling equations in cylindrical coordinates.

Composite Aramid Membranes with High Strength and pH-Response.

The pH-responsive membrane is a new wastewater treatment technology developed in recent years. In this paper, a novel film with intelligent pH-responsiveness was first prepared by blending functional gates comprised of hydrolyzed aramid nanofibers (HANFs) into aramid nanofiber (ANF) membranes via a vacuum filtration method. Those as-prepared membranes exhibited dual pH-responsive characteristics, which were featured with a negative pH-responsiveness in an acidic environment and a positive pH-responsiveness in basic media.