Time-Dependent Solvent-Driven Solid-State Fluorescence-based Numeric Coding.

Controllable solid-state transformations can provide a basis for novel functional materials. Herein, we report a series of solid-state systems that can be readily transformed between amorphous, co-crystalline, and mixed crystalline states via grinding or exposure to solvent vapors. The present solid materials were constructed using an all-hydrocarbon macrocycle, cyclo[8](1,3-(4,6-dimethyl)benzene) () (host), and neutral aggregation-caused quenching dyes (guests), including 9,10-dibromoanthracene (), 1,8-naphtholactam (), diisobutyl perylene-3,9-dicarboxylate (), 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza--indacene (), 4,7-di(2-thienyl)-benzo[2,1,3]thiadiazole (), and 4-imino-3-(pyridin-2-yl)-4-quinolizine-1-carbonitrile ().

A Mild Silica Gel Promoted Synthesis and Initial Functional Study of Tetrapyridyl Tetrahydropyrrolopyrrolones.

A one-pot strategy with yields up to 82% was reported to generate 2-(pyridin-2-yl)-2-(3,3a,6-tris(5-pyridin-2-yl)-5-oxohexahydropyrrolo[3,2-] pyrrol-2(1)-ylidene)acetonitrile and its derivatives -. Silica gel promoted quantitative conversion from stable intermediate to within 30 min at room temperature. Finally, four chemical σ bonds and two chiral carbons with high diastereoselectivity were achieved.

A DNA small molecular probe with increasing K concentration promoted selectivity.

DNA small molecular probe study was considered as a promising approach to achieve DNA related disease diagnosis. Most related reports were performed under specific salinity. Herein, 4-imino-3-(pyridin-2-yl)-4-quinolizine-1-carbonitrile (IPQC) was generated a facile procedure with high yield (85%).

One-Pot Synthesis of 3-Substituted 4-Quinolizin-4-ones via Alkyne Substrate Control Strategy.

Three-substituted 4-quinolizin-4-ones were obtained via a facile method with good selectivity and high efficiency. On the basis of alkyne substrate control, the mild and cost-efficient reaction has a broad substrate scope (20 examples, up to 93% yield) and is also easy to scale up. Active sites on the products allow for further modifications.