From an early age, humans learn to develop an intuition for the physical nature of the objects around them by using exploratory behaviors. Such exploration provides observations of how objects feel, sound, look, and move as a result of actions applied on them. Previous works in robotics have shown that robots can also use such behaviors (e.
View Article and Find Full Text PDFBackground: Identification of functionally important sites in biomolecular sequences has broad applications ranging from rational drug design to the analysis of metabolic and signal transduction networks. Experimental determination of such sites lags far behind the number of known biomolecular sequences. Hence, there is a need to develop reliable computational methods for identifying functionally important sites from biomolecular sequences.
View Article and Find Full Text PDFBackground: Glycosylation is one of the most complex post-translational modifications (PTMs) of proteins in eukaryotic cells. Glycosylation plays an important role in biological processes ranging from protein folding and subcellular localization, to ligand recognition and cell-cell interactions. Experimental identification of glycosylation sites is expensive and laborious.
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