Polymorphisms of the human IL-1 receptor antagonist gene and forearm bone mineral density in postmenopausal women.

Context: Studies on the human interleukin 1 receptor antagonist (IL-1RA) gene polymorphism have provided conflicting data regarding the bone mass and quality.

Aim And Design: The objective of this case-control study was to investigate the association between the forearm bone mineral density (BMD) and the IL1RA gene polymorphisms.

Materials And Methods: A total of 400 postmenopausal Bulgarian women participated in this study.

PvuII and XbaI polymorphisms of the estrogen receptor gene and bone mineral density in a Bulgarian population sample.

Objective: The aim of this study was to search for a possible association of low bone mineral density (bMD) with the PvuII and XbaI polymorphisms of the estrogen receptor (Er) gene in bulgarian women.

Design: 400 bulgarian women participated in this study. bMD was measured at the lumbar spine, femoral neck and at the distal forearm.