Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction.

Functional magnetic resonance imaging-based functional connectivity enables the non-invasive mapping of individual differences in brain functional organization to individual differences in a vast array of behavioral phenotypes. This flexibility has renewed the search for neuroimaging-based biomarkers that exhibit reproducibility, prediction, and precision. Functional connectivity-based measures that share these three characteristics are key to achieving this goal.

Increasing the representation of minoritized youth for inclusive and reproducible brain-behavior associations.

Population neuroscience datasets allow researchers to estimate reliable effect sizes for brain-behavior associations because of their large sample sizes. However, these datasets undergo strict quality control to mitigate sources of noise, such as head motion. This practice often excludes a disproportionate number of minoritized individuals.

Right fronto-parietal networks mediate the neurocognitive benefits of enriched environments.

Exposure to enriched environments throughout a lifetime, providing so-called reserve, protects against cognitive decline in later years. It has been hypothesized that high levels of alertness necessitated by enriched environments might strengthen the right fronto-parietal networks to facilitate this neurocognitive resilience. We have previously shown that enriched environments offset age-related deficits in selective attention by preserving grey matter within right fronto-parietal regions.

The association between inadequate sleep and accelerated brain ageing.

Numerous studies indicate large heterogeneity in brain ageing, which can be attributed to modifiable lifestyle factors, including sleep. Inadequate sleep has been previously linked to gray (GM) and white (WM) matter changes. However, the reported findings are highly inconsistent.