Publications by authors named "Jiulong An"

Article Synopsis
  • Calcium homeostasis imbalance can lead to chronic diseases, making effective calcium supplements crucial for health.
  • The study focused on identifying peptide calcium chelates from soybean peptides to enhance calcium absorption while minimizing side effects.
  • Two specific peptides (GGDLVS and YEGVIL) were found to exhibit high calcium binding capacity, and the research aimed to clarify how the amino acid positions influence this binding efficiency.
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α-Amylase inhibitory peptides are used to treat diabetes, but few studies have statistically characterized their interaction with α-amylase. This study performed the molecular docking of α-amylase with inhibitory peptides from published papers. The key sites, side chain chargeability, and hydrogen bond distribution characteristics were analyzed.

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Calcium is one of the most important mineral elements in the human body and is closely related to the maintenance of human health. To prevent calcium deficiency, various calcium supplements have been developed, but their application tends to be limited by low calcium content and highly irritating effects on the stomach, among other side effects. Recently, calcium-peptide chelates, which have excellent stability and are easily absorbed, have received attention as an alternative emerging calcium supplement.

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Inflammation is considered to be a crucial factor in the development of chronic diseases, eight of which were listed among the top ten causes of death worldwide in the World Health Organization's World Health Statistics 2019. Moreover, traditional drugs for inflammation are often linked to undesirable side effects. As gentler alternatives to traditional anti-inflammatory drugs, plant-derived bioactive peptides have been shown to be effective interventions against various chronic diseases, including Alzheimer's disease, cardiovascular disease and cancer.

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