LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis.

Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-related deaths. As a critical regulator of the Hippo pathway, the phosphorylation status of Yes-associated protein 1 (YAP1), mainly at S127, is critical for its oncogenic function. Herein, we aim to investigate the precise molecular mechanism between long noncoding RNA HOX transcript antisense RNA (HOTAIR) and YAP1 phosphorylation in regulating tumor migration and invasion.

Construction and optimization of ecological networks based on future scenario simulation in Qianshan City, Anhui Province.

The rapid urbanization adversely affects landscape pattern of mountainous cities. It is of great practical significance to explore the spatial and temporal evolution of ecological networks in mountainous areas to achieve regional ecological security. Taking Qianshan City in Anhui Province as an example, based on the land use data in 2012 and 2020, we simulated the land use situation in 2036 with PLUS model, and constructed the ecological networks in 2020 and 2036, respectively.

Research on land-use evolution and ecosystem services value response in mountainous counties based on the SD-PLUS model.

Rapid urbanization has caused changes in climate and environment and threatened the ecosystem with multiple risks. The ecosystem services capacity has shown a downward trend accordingly. It is significant to explore the spatio-temporal evolution of land use and ecosystem services value (ESV) in mountainous counties at small scales, as it coordinates economic growth and ecological protection, and promotes sustainable and high-quality development.

Association between prenatal or postpartum exposure to tobacco smoking and allergic rhinitis in the offspring: An updated meta-analysis of nine cohort studies.

Introduction: Previous studies have suggested an association between tobacco smoke exposure and allergic rhinitis. This study aimed to investigate if prenatal or postpartum smoke exposure will increase the risk of allergic rhinitis in offspring.

Methods: PubMed, EMBASE, and the Cochrane library were searched from inception to July 2020 for eligible studies investigating the association between smoking exposure and allergic rhinitis.

[Age structure and dynamics of Keteleeria davidiana var. chien-peii population in Guizhou Province].

Type and dynamics of age structure of Keteleeria davidiana var. chien-peii population and its relationship to community succession and environment were analyzed. The results showed that the age structures were classified into four types:growing, stable, initial and middle sensecent types.