subsp. FJSYZ1M3 ameliorates DSS-induced colitis by maintaining the intestinal barrier, regulating inflammatory cytokines, and modifying gut microbiota.

subsp. is a subspecies of , and very few strains are shown to have immunomodulatory effects. In the present study, the improvement of dextran sulphate sodium (DSS)-induced colitis by four subsp.

Ameliorates Dextran Sulfate Sodium-Induced Colitis by Producing Conjugated Linoleic Acid, Protecting Intestinal Mechanical Barrier, Restoring Unbalanced Gut Microbiota, and Regulating the Toll-Like Receptor-4/Nuclear Factor-κB Signaling Pathway.

This study aimed to explore the effects and differences of conjugated linoleic acid (CLA)-producing on the alleviation of dextran sulfate sodium (DSS)-induced colitis and to explore its patterns. Different strains were administered at 10 cfu/day 7 days before DSS treatment. CCFM681 significantly increased goblet cells, mucin2 (MUC2), claudin-3, α-catenin1, and ZO-1, but neither CCFM760 nor CCFM642 had those protective effects.