Publications by authors named "Jitteke de Jong"
Background And Aims: Histological outcomes and JAK-STAT signalling were assessed in a prospective ulcerative colitis [UC] patient cohort after 8 weeks treatment with tofacitinib, an oral Janus kinase [JAK] inhibitor.
Methods: Forty UC patients received tofacitinib 10 mg twice daily for 8 weeks. Treatment response was defined as histo-endoscopic mucosal improvement [HEMI].
Article Synopsis
- A study was conducted to evaluate the effectiveness of pan-enteric capsule endoscopy (pan-CE) in measuring mucosal changes in Crohn's disease patients undergoing biologic treatment.
- Twenty-two patients participated, with results showing that 27% achieved endoscopic remission and 59% showed an endoscopic response after treatment.
- The median scores of disease activity significantly decreased, indicating that pan-CE is an effective tool for monitoring mucosal disease activity in Crohn's patients without reported adverse events.