An Aggregation-Induced Emission Nanosensor for Real-Time Chemiluminescent Sensing of Light-Independent Intracellular Singlet Oxygen.

Characterizing the transient ultratrace light-independent intracellular singlet oxygen (O), which plays a vital role in multiple biological processes in living organisms, brings about tremendous help for understanding the nature of O-mediated or related bioevents. Nevertheless, an approach to detect the light-independent intracellular O is hard to find. Herein, we developed a chemiluminescent nanosensor by compacting a great number of TPE-N(Ph)-DBT-PH molecules in one nanostructure via autoaggregation.

A visual volumetric hydrogel sensor enables quantitative and sensitive detection of copper ions.

We propose a visual volumetric sensor with 5,6-dicarboxylic fluorescein cross-linked amine-functionalized polyacrylamide hydrogel. The sensor undergoes volume response to Cu(2+) ions at the μM level, which enables naked-eye quantitative detection by reading the graduation on a pipette.