The application of sp., a fungus that commonly thrives on complex agricultural and plant wastes, has proven successful in utilizing citrus peel waste as a source of naringin. A UV-Vis spectrophotometric method proved the biotransformation of naringin, with an absorption maximum (λ) observed at 310 nm for the biotransformed product, naringenin (NAR).
View Article and Find Full Text PDFNaringinase is an important enzyme for commercial purposes due to its dual activity as both α-l-rhamnosidase and β-d-glucosidase. The traditional method for screening microbes that produce naringinase involves growing them on naringin agar, but this method has limitations and result in false positive results. This is because the growth on the naringin agar plate could be due to the presence of other organisms that produce rhamnosidase or other glucosidases, or those that use agar as a carbon source, rather than actual naringinase producers.
View Article and Find Full Text PDFSevere ocular infections by sp. lead to keratitis, resulting in irreversible vision loss in immune-compromised individuals. When a protozoal infection spreads to neural tissues, it causes granulomatous encephalitis, which can be fatal.
View Article and Find Full Text PDFThe development of resistance, instability and high doses are some drawbacks of biologically active natural products. Modification of natural compounds to make it broad spectrum is the standard approach in drug design. This paper sets to modify the naringenin by silver nanoparticle conjugation to enhance its already reported pharmacological activities.
View Article and Find Full Text PDF