Piperine improves the health span of Drosophila melanogaster with age- and sex-specific effect.

Piperine, a dietary phytochemical isolated from the Piper species, has been used as a natural medicine for pain, flu, and fever in ancient China and India. Although the health benefits of piperine have been widely studied, research on its effect on aging is limited. This study aimed to determine whether piperine has the potential to mitigate aging-related changes in the fruit fly (Drosophila melanogaster), which is an excellent model organism for studies on aging.

Bioinspired -Naphthoquinone-Catalyzed Aerobic Oxidation of Alcohols to Aldehydes and Ketones.

A biomimetic alcohol dehydrogenase (ADH)-like oxidation protocol was developed using an -naphthoquinone catalyst in the presence of a catalytic amount of base. The developed organocatalytic aerobic oxidation protocol proceeds through the intramolecular 1,5-hydrogen atom transfer of naphthalene alkoxide intermediates, a mechanistically distinctive feature from the previous alcohol dehydrogenase mimics that require metals in the active form of catalysts. The ADH-like aerobic oxidation protocol should provide green alternatives to the existing stoichiometric and metal-catalyzed alcohol oxidation reactions.

The impact of employment protection on health: Evidence from fixed-term contract workers in South Korea.

In this paper, we examine the impact of increased employment protection on the self-rated health of workers. We utilize the recent labor reform in South Korea which sharply increased the employment protection level of fixed-term contract workers meeting certain criteria. By applying a difference-in-differences framework to longitudinal data, we explore the causal impact of employment protection.

Spectral domain optical coherence tomography findings in bilateral peripheral cone dystrophy.

Introduction: To report spectral domain optical coherence (OCT) tomography findings in a case of bilateral peripheral cone dystrophy.

Case Report: A 21-year-old man complained of blurred visual fields on the lateral sides of both eyes. The patient's best-corrected visual acuity was 20/20 in both eyes.