Fully 3D-Printed Soft Capacitive Sensor of High Toughness and Large Measurement Range.

Soft capacitive sensors are widely utilized in wearable devices, flexible electronics, and soft robotics due to their high sensitivity. However, they may suffer delamination and/or debonding due to their low interfacial toughness. In addition, they usually exhibit a small measurement range resulting from their limited stiffness variation range.

Activating FeMoO nanosheet arrays by partial nickel substitution for efficient electrocatalytic seawater oxidation.

Nickel-substituted FeMoO nanosheet arrays assembled on a nickel foam skeleton are fabricated by a spontaneous redox reaction. Due to the synergistic effect of the increase of exposed active sites and improvement of electron transfer, the targeted catalyst exhibits excellent electrocatalytic performance for seawater oxidation.

Endoplasmic Reticulum-Targeting AIE Photosensitizers to Boost Immunogenic Cell Death for Immunotherapy of Bladder Carcinoma.

Bladder cancer is characterized by high rates of recurrence and multifocality. Immunogenic cell death (ICD) of cancer cells has emerged as a promising strategy to improve the immunogenicity of tumor cells for enhanced cancer immunotherapy. Although photosensitizer-based photodynamic therapy (PDT) has been validated as capable of inducing ICD in cancer cells, the photosensitizers with a sufficient ICD induction ability are still rare, and there have been few reports on the development of advanced photosensitizers to strongly evoke the ICD of bladder cancer cells for eliciting potent antitumor immune responses and eradicating bladder carcinoma in situ.

π-π Interaction-Induced Organic Long-wavelength Room-Temperature Phosphorescence for In Vivo Atherosclerotic Plaque Imaging.

Room-temperature phosphorescent (RTP) materials have great potential for in vivo imaging because they can circumvent the autofluorescence of biological tissues. In this study, a class of organic-doped long-wavelength (≈600 nm) RTP materials with benzo[c][1,2,5] thiadiazole as a guest was constructed. Both host and guest molecules have simple structures and can be directly purchased commercially at a low cost.

Interfacial engineering of CoP/CoS heterostructure for efficiently electrocatalytic pH-universal hydrogen production.

The design and development of high-performance, low-cost catalysts with long-term durability are crucial for hydrogen generation from water electrolysis. Interfacial engineering is an appealing strategy to boost the catalytic performance of electrode materials toward hydrogen evolution reaction (HER). Herein, we report a simple phosphidation followed by sulfidation treatment to construct heterogeneous cobalt phosphide-cobalt sulfide nanowire arrays on carbon cloth (CoP/CoS/CC).

Rare Complication of Massive Depigmentation After Postoperative Treatment of Giant Keloid Combined With Strontium-90.

Post-acne keloids have become a serious problem affecting the physical and mental health of adolescents. However, traditional single-treatment methods have a high recurrence rate and are highly susceptible to a variety of complications. Postoperative radiotherapy has rapidly become a popular choice for comprehensive postoperative treatment because of its painlessness, non-invasiveness, convenience, low recurrence rate, and few complications.

Skin Mixed Tumor of Right Nose.

Skin mixed tumors are extremely rare clinically, lack characteristic manifestations, and are easily confused with other diseases. An Asian male came to our hospital's cosmetic and plastic surgery department because of a skin mass on the right side of his nose. After unanimous discussion by our doctors, the patient underwent subcutaneous tumor resection under local anesthesia and rotational flap transplantation to treat the disease and improve the shape of the nose.

Dual-metal-organic-framework derived CoP/MoP hybrid as an efficient electrocatalyst for acidic and alkaline hydrogen evolution reaction.

Searching for efficient and cost-effective electrocatalysts for hydrogen evolution reaction (HER) is significantly desirable and challenging. Herein, N, P co-doped carbon-encapsulated CoP/MoP hybrid (CoP/MoP@NPC) is fabricated using dual-metal-organic-framework (dual-MOF) as precursor by a simple one-step phosphating process. When applied as an electrocatalyst toward the HER, the as-designed CoP/MoP@NPC hybrid shows efficiently catalytic performance with a lower overpotential of 183 mV to deliver a current density of 10 mA cm, smaller Tafel slope of 53.

The facile synthesis of FeP/CoP confined in N, P co-doped carbon derived from MOFs for an efficient pH-universal hydrogen evolution reaction.

Electrochemical hydrogen production is greatly limited by the low efficiency, high cost, and poor stability of electrocatalysts. Here, we report a facile one-step method to synthesize nitrogen, phosphorus co-doped carbon encapsulated FeP/CoP derived from dual metal-organic frameworks (FeP/CoP@NPC). Thanks to the synergistic effect of its unique composition and structure, the resultant FeP/CoP@NPC shows excellent catalytic HER performance with low potentials of 198, 286, and 339 mV to achieve a current density of 10 mA cm in acidic, neutral, and alkaline media along with remarkable long-time durability, respectively.

Silver decorated nickel-cobalt (oxy)hydroxides fabricated surface reconstruction engineering for boosted electrocatalytic oxygen evolution and urea oxidation.

Electrochemical water splitting is considered to be a promising renewable hydrogen generation technology but is significantly limited by the kinetically sluggish oxygen evolution reaction (OER) at the anode. Herein, a silver nanoparticle decorated nickel-cobalt (oxy)hydroxide composite is fabricated on nickel foam (Ag@NiCo(OH)/NF) electrodeposition followed by spontaneous redox reaction. Benefitting from the synergetic contributions of an amorphous/crystalline phase, abundant artificial heterointerfaces, and a 3D porous architecture, the as-designed Ag@NiCo(OH)/NF shows substantially enhanced electrocatalytic performance toward the OER and urea oxidation reaction.

Neuroprotective, Anti-inflammatory Effect of Furanochrome, Visnagin Against Middle Cerebral Ischemia-Induced Rat Model.

In recent years, the medical field had significantly progressed to a greater extent which was evidenced with increased life expectancy and decreased mortality rate. Due to the growth of medical field, numerous communicable diseases are prevented and eradicated, whereas the non-communicable disease incidence has been increased globally. One such non-communicable disease which threatens the global population is stroke.

Double-Cavity Nor-Seco-Cucurbit[10]uril Enables Efficient and Rapid Separation of Pyridine from Mixtures of Toluene, Benzene, and Pyridine.

Benzene, toluene and pyridine are widely used as essential raw materials in industry and laboratory research, with stringent purity requirements. Herein, we show that solid double-cavity host nor-seco-cucurbit[10]uril (ns-Q[10]) functions as an efficient adsorption separator for pyridine; benzene and toluene can be obtained in >99.9 % purity by this method.

MOF-derived ruthenium-doped amorphous molybdenum dioxide hybrid for highly efficient hydrogen evolution reaction in alkaline media.

Ruthenium-doped amorphous molybdenum dioxide coupled with a reduced graphene oxide hybrid (Ru-MoO@PC/rGO) is synthesized using polyoxometalate-based MOFs/GO as a precursor. Benefitting from the synergistic effect of numerous exposed active sites, Ru dopants and the introduction of GO, the designed catalyst shows exceptional electrocatalytic performance toward the HER in alkaline media.

Engineering MoC nanoparticles confined in N,P-codoped porous carbon hollow spheres for enhanced hydrogen evolution reaction.

N,P-codoped porous carbon hollow nanosphere confining ultrafine molybdenum carbide nanoparticles are designed and prepared through a facile method. By virtue of the distinct composite and structure advantages, the resulting composite shows significantly enhanced electrocatalytic performance toward the hydrogen evolution reaction.

Synergistically enhanced hydrogen evolution reaction by ruthenium nanoparticles dispersed on N-doped carbon hollow nanospheres.

Ultrafine Ru nanoparticles dispersed on 3D N-doped carbon hollow nanospheres were firstly prepared by a feasible templating strategy. Due to the synergistic effect of the unique composite and structure, the resulting nanocomposite as a HER catalyst shows extraordinary electrocatalytic performance, superior to that of commercial Pt-C and most previously reported electrocatalysts.

Substituent-controlled chemoselective synthesis of multi-substituted pyridones via a one-pot three-component cascade reaction.

An efficient and concise one-pot strategy for the synthesis of multisubstituted pyridones via a one-pot three-component cascade reaction catalyzed by CsCO under solvent-free conditions has been developed. The substituent-controlled chemoselective cycloaddition process involved steps including a Michael addition/ethanol elimination/intermolecular cyclization sequence utilizing anilines, diethyl acetylenedicarboxylate, and diethyl ethoxymethylenemalonate. In doing so, various 2-pyridone and 4-pyridone species (41 examples) could be obtained in good to excellent yields.

Ruthenium Nanoparticles Anchored on Graphene Hollow Nanospheres Superior to Platinum for the Hydrogen Evolution Reaction in Alkaline Media.

The design and construction of highly efficient and stable Pt-free catalysts for the electrocatalytic hydrogen evolution reaction (HER) in alkaline media is extremely desirable. Herein, a novel hybrid of ruthenium (Ru) nanoparticles anchored on graphene hollow nanospheres (GHSs) is synthesized by a template-assisted strategy. The combination of ultrafine Ru nanoparticles and hollow spherical support endows the resultant Ru/GHSs an extraordinary catalytic performance with a low overpotential of 24.

Confined Molybdenum Phosphide in P-Doped Porous Carbon as Efficient Electrocatalysts for Hydrogen Evolution.

Highly efficient electrocatalysts for hydrogen evolution reactions (HER) are crucial for electrochemical water splitting, where high-cost and low-abundance Pt-based materials are the benchmark catalysts for HER. Herein, we report the fabrication of MoP nanoparticles confined in P-doped porous carbon (MoP@PC) via a metal-organic framework-assisted route for the first time. Remarkably, due to the synergistic effects of MoP nanocrystals, P dopant, and porous carbon, the resulting MoP@PC composite exhibits superior HER catalytic activity with an onset overpotential of 97 mV, a Tafel slope of 59.

Assembly of Multifold Helical Polyoxometalate-Based Metal-Organic Frameworks as Anode Materials in Lithium-Ion Batteries.

For exploring the multifold helical fabrication of polyoxometalate (POM)-based hybrid compounds, four POM-based crystalline compounds with different meso-helices, H[Ag(trz)(HO)][SiWO]·5HO (1), H[Ag(trz)(HO)][PWO]·2HO (2), [Ag(trz)(HO)][HSiWO] (3), and [Ag(trz)(HO)][PWO] (4), were successfully isolated by using the delicate 1,2,3-triazole ligand and silver ions in this work. Crystal analysis reveals that compounds 1 and 2 and compounds 3 and 4 are isomorphous and display 2-/4-fold mixed meso-helices and simple 2-fold meso-helices, respectively. In addition, due to the reversible multielectron redox behavior and electron storage functions of POMs, compounds 1 and 3 were studied as anode materials in lithium-ion batteries (LIBs).

High Number of Circulating Tumor Cells Predicts Poor Survival of Cutaneous Melanoma Patients in China.

BACKGROUND Melanoma is an aggressive cancer with complex etiology and poor prognosis. Surgical resection is still the primary treatment of melanoma, but shows limited efficacy in late-stage patients. Additionally, reliable prognostic markers of skin melanoma patients are still lacking.

Highly efficient hydrogen evolution electrocatalysts based on coupled molybdenum phosphide and reduced graphene oxide derived from MOFs.

A coupled hybrid of molybdenum phosphide (MoP) and reduced graphene oxide has been prepared for the first time utilizing Mo-MOFs as precursors through a facile method. The nanocomposite exhibits superior electrocatalytic performance towards the HER, and is one of the best high-performance MoP-based electrocatalysts under acidic conditions reported so far.

High expression of CD47 predicts adverse prognosis in Chinese patients and suppresses immune response in melanoma.

Background: Cluster of differentiation 47 (CD47) negatively regulates macrophage phagocytosis and is correlated with adverse survival of multiple cancers. In melanoma patients, especially in Chinese melanoma patients, its prognostic value is unclear. In this study, we aim to study the prognostic value of CD47 in a Chinse melanoma patient cohort and its immunomodulation roles in mouse model.

Polyoxometalate-Incorporated Metallapillararene/Metallacalixarene Metal-Organic Frameworks as Anode Materials for Lithium Ion Batteries.

A series of remarkable crystalline compounds containing metallapillararene/metallacalixarene metal-organic frameworks (MOFs), [Ag(pyttz)·Cl·(HO)][HSiMoO]·3HO (1), [Ag(trz)][HSiMoO] (2), [Ag(trz)][HGeMoO] (3), and [Ag(trz)][HPWO] (4) (pyttz = 3-(pyrid-4-yl)-5-(1H-1,2,4-triazol-3-yl)-1,2,4-triazolyl, trz = 1,2,4-triazole), have been obtained by using a simple one-step hydrothermal reaction of silver nitrate, pyttz for 1 and trz for 2-4, and Keggin type polyoxometalates (POMs). Crystal analysis reveals that Keggin POMs have been successfully incorporated in the windows of the metallapillararene/metallacalixarene MOFs in compounds 1-4. In addition, the Keggin silicomolybdenate-based hybrid compounds 1 and 2 were used as anode materials in lithium ion batteries (LIBs), which exhibited promising electrochemical performance with the first discharge capacities of 1344 mAh g for 1 and 1452 mAh g for 2, and this stabilized at 520 mAh g for 1 and 570 mAh g for 2 after 100 cycles at a current density of 100 mA g.

Electrochemical sensor for detection of hydrogen peroxide modified with prussian blue electrodeposition on nitrogen, phosphorus and sulfur co-doped porous carbons-chitosan.

Nitrogen, phosphorus and sulfur co-doped porous carbons (N, P, S@PC) were well dispersed in the chitosan (CS) acid solution, in particular via covalently interaction, which could avoid the aggregation of N, P, S@PC in most solvents. Moreover, CS could also avoid N, P, S@PC leakage from the modified electrode. A novel electrochemical sensor was then developed through prussian blue (PB) was electrodeposited on the glass carbon (GC) electrode modified with N, P, S@PC-CS composite.