The release of metal elements from litter decomposition in forest ecosystems is crucial for material cycling and ecosystem health, but the impact of future variations in rainfall due to climatic fluctuations on this release is unknown. This study conducted an outdoor rainfall variability simulation and an in situ litter decomposition experiment in a subtropical location, with a focus on pure Pinus massoniana (PM) and 4 p.m.
View Article and Find Full Text PDFPurpose: This study was the first to evaluate the effect of CYP3A5*3 gene polymorphisms on plasma concentration of perampanel (PER) in Chinese pediatric patients with epilepsy.
Methods: We enrolled 98 patients for this investigation. Plasma PER concentrations were measured using liquid chromatography-tandem mass spectrometry.
Background: Information on the efficacy and plasma concentration of perampanel (PER) in Chinese pediatric patients with epilepsy is limited. Therefore, this real-world retrospective study aimed to assess the efficacy, tolerability, and plasma concentration of the maximum dose of PER for epilepsy treatment in Chinese pediatric patients.
Methods: A total of 107 pediatric patients from 2 hospitals in China were enrolled in this study.
The safety and effectiveness of perampanel in clinical settings involving Chinese pediatric patients are limited, as perampanel has only recently been approved for use in China, in September 2019. We aimed to evaluate the efficacy and tolerability of perampanel as an adjunctive therapy for pediatric patients with epilepsy aged ≥ 4 years in Xinjiang, Northwest China. Efficacy was assessed by measuring changes in seizure frequency at 3-, 6-, and 12-month follow-up compared with baseline.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
January 2019
Objective: To investigate the development of social skills in children with autism spectrum disorder (ASD) and related influencing factors.
Methods: A total of 889 children with ASD in 10 cities of China were enrolled as subjects. The Autism Social Skills Scale was used to assess their social skills.