Publications by authors named "Jiraporn Wongyai"
Medication non-adherence in tuberculosis (TB) patients is an obstacle to TB treatment. Directly observed treatment to monitor and ensure adherence still has some limitations in high TB-burden countries. Most digital adherence technologies emphasize medication-taking reminder functions; however, a bi-directional communication platform to provide patient-health workers with an interface that focuses on enhancing medication adherence is likely to improve medical adherence.
View Article and Find Full Text PDFThe current Thai guideline recommends that among people living with HIV, isoniazid preventive therapy (IPT) should be given to those with a positive tuberculin skin test (TST). We conducted a case-control study, nested within a cohort study, in Chiang Rai Province in Thailand to determine the role of TST in predicting the development of active tuberculosis (TB) within the following 2 years. Comparison between participants with CD4+ counts <50cells/mm to those with CD4+ ≥200cells/mm revealed that TST results were less sensitive (7.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the global population of *Mycobacterium tuberculosis*, identifying 7 major lineages, with a focus on the globally prevalent Modern Beijing strains linked to drug resistance and outbreaks.
- Analysis of 1170 whole genome sequences revealed new sublineages and significant associations with patient demographics, such as age, ethnicity, and HIV status, indicating varied prevalence across different populations.
- Notably, certain ancestral strains and rare sublineages were tied to specific ethnic groups in Southern China, suggesting a gradual evolution to Modern Beijing strains fueled by diverse ethnic interactions.
Background: The neutrophil to lymphocyte ratio (NL ratio) has been reported to be a predictive biomarker of tuberculosis (TB). We assessed the association between the NL ratio and the incidence of active TB cases within 1 year after TB screening among HIV-infected individuals in Thailand.
Methods: A day care center that supports HIV-infected individuals in northernmost Thailand performed TB screening and follow-up visits.
Tuberculosis presents a global health challenge. Mycobacterium tuberculosis is divided into several lineages, each with a different geographical distribution. M.
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