Anesthetic Agents as Therapeutic Tools in Breast Cancer: Insights into Cancer Progression and Recurrence.

Breast cancer (BC) remains one of the leading causes of cancer-related mortality worldwide, necessitating continuous advancements in therapeutic strategies. While anesthetic agents are traditionally used for managing pain and sedation during BC surgeries, emerging evidence suggests their potential influence on cancer progression and recurrence. This comprehensive review examines the role of various anesthetic agents as therapeutic tools in BC, exploring the molecular mechanisms underlying their interaction with tumor biology.

Case report: Novel mutations in the SPG11 gene in a case of autosomal recessive hereditary spastic paraplegia with a thin corpus callosum.

A 24-year-old man presented with insidious onset progressive gait disturbance and was finally diagnosed with autosomal recessive hereditary spastic paraplegia. Two novel mutations, including a frameshift mutation (c.5687_5691del) and a non-sense mutation (c.