Intermittent fasting for weight management and metabolic health: An updated comprehensive umbrella review of health outcomes.

Aims: To provide an updated comprehensive evaluation of the quality and evidence association of existing studies on health outcomes related to intermittent fasting (IF).

Materials And Methods: We conducted a systematic search of PubMed, Web of Science, Cochrane Library, and Embase databases, covering literature up to June 2024. Meta-analyses and systematic reviews that include adult populations and quantitatively analyse health outcomes related to IF interventional studies are included.

Ziprasidone population pharmacokinetics and co-medication effects in Chinese patients.

Ziprasidone is widely used in the treatment of psychiatric disorders. Despite its prevalence, there is a notable lack of population pharmacokinetics (PPK) studies on ziprasidone in serum, both domestically and internationally. This study aimed to comprehensively investigate the various factors influencing the PPK characteristics of Ziprasidone, thereby providing a scientific basis for personalized treatment strategies in clinical settings.

Contrasting laboratory and field outcomes of bat-moth interactions.

Predator-prey interactions are important but difficult to study in the field. Therefore, laboratory studies are often used to examine the outcomes of predator-prey interactions. Previous laboratory studies have shown that moth hearing and ultrasound production can help prey avoid being eaten by bats.

Fabrication high toughness poly(butylene adipate-co-terephthalate)/thermoplastic starch composites via melt compounding with ethylene-methyl acrylate-glycidyl methacrylate.

The preparation of biodegradable composites with high toughness and low cost is of great significance for their application and promotion in the packaging field. As a renewable and biodegradable material with abundant sources, the inclusion of starch in biodegradable composites can significantly reduce costs. However, the poor compatibility between starch and matrix severely limits its large-scale practical application.

[Research progress on Chinese herbal medicine fermentation and profile of active substances derived].

Chinese herbal medicines( CHMs) are a class of preparations made from natural plants that pose health beneficial properties as well as illness prevention functions. Thanks to a panel of salutary features,such as comprehensive immunological enhancement and inhibition of pathogenic bacteria,negligible side-effects,inappreciable drug-resistance,CHMs have been taken as one of the costeffective candidates for antibiotics substitutions. Through probiotics fermentation,the enzymatic hydrolysis of matrixes of CHMs enables easier release of the active ingredient as well as endows less toxicity of the preparations derived.

A Facile Fabrication of High Toughness Poly(lactic Acid) via Reactive Extrusion with Poly(butylene Succinate) and Ethylene-Methyl Acrylate-Glycidyl Methacrylate.

As is an excellent bio-based polymer material, poly(lactic acid) (PLA)'s brittle nature greatly restricts its extensive applications. Herein, poly(butylene succinate) (PBS) was introduced to toughening PLA by melt blending using a self-made triple screw extruder through in situ reactive with ethylene-methyl acrylate-glycidyl methacrylate (EGMA). The effect of EGMA concentrations on the mechanical properties, morphology, interfacial compatibility of PLA/PBS blends were studied.

In vivo and in vitro antiviral effects of berberine on influenza virus.

Objective: To explore the potential effects of berberine on influenza virus infection both in vitro and in vivo.

Methods: In vitro anti-influenza virus assays were performed by cytopathogenic effect and neuraminidase assays in Madin Darby canine kidney cells. In vivo anti-influenza virus assays were performed on the viral pneumonia model of mice.