Clinicopathological and prognostic value of epithelial cell adhesion molecule in solid tumours: a meta-analysis.

Background: Malignant tumors, mainly solid tumors, are a significant obstacle to the improvement of life expectancy at present. Epithelial cell adhesion molecule (EpCAM), a cancer stem cell biomarker, showed widespread expression in most normal epithelial cells and most cancers. Although the clinical significance of EpCAM in various malignant solid tumors has been studied extensively, the latent relationships between EpCAM and pathological and clinical characteristics in solid tumors and differences in the roles of EpCAM among tumors have not been clearly determined.

Head-to-head comparison of Ga-FAPI-04 PET/CT and F-FDG PET/CT in the evaluation of primary digestive system cancer: a systematic review and meta-analysis.

Introduction: Althoug F-FDG positron emission tomography/computed tomography (PET/CT) is widely accepted as a diagnostic tool for detecting digestive cancers, Ga-FAPI-04 PET/CT may perform better in detecting gastrointestinal malignancies at an earlier stage. This study aimed to systematically review the diagnostic performance of Ga-FAPI-04 PET/CT compared with that of F-FDG PET/CT in primary digestive system cancers.

Methods: In this study, a comprehensive search using the PubMed, EMBASE, and Web of Science databases was performed to identify studies that met the eligibility criteria from the beginning of the databases to March 2023.