[Hydrochemical and Stable Isotopic Characteristics and Transformation Relationship of Water Bodies in the Guohe River Basin, Anhui Province].

The Guohe River Basin in Anhui Province was selected as the research area for this study. By collecting surface water, shallow groundwater, and middle-deep groundwater samples, various hydrochemical parameters and stable isotopes of water in different water bodies were analyzed using methods such as the Gibbs diagram, ion ratios, and MixSIAR model to reveal and quantify the transformation relationships between these water bodies. The results indicated that both surface water and groundwater in the study area were predominantly neutral to weakly alkaline.

Distribution, source identification, water quality, and risk assessment of trace elements in the surface-groundwater-sediments multifunctional system in Guohe River Basin.

Within the Huaihe River Basin, Guohe River, as its second-largest tributary, serves as a critical water supply source. Recent industrial and agricultural advancements have led to increased trace element contamination, adversely impacting the water quality within Guohe River Basin. Therefore, this study aimed to investigate the distribution characteristics, sources, water quality and risk assessment of trace elements in the surface water, groundwater, and sediments across the basin.

Hydrochemistry, quality, and integrated health risk assessments of groundwater in the Huaibei Plain, China.

Groundwater is an essential freshwater resource utilized in industry, agriculture, and daily life. In the Huaibei Plain (HBP), where groundwater significantly influences socio-economic development, information about its quality, hydrochemistry, and related health risks remains limited. We conducted a comprehensive groundwater sampling in the HBP and examined its rock characteristics, water quality index (WQI), and potential health risks.

Effect of high-intensity ultrasound on the structural and functional properties of proteins in housefly larvae (Musca demestica).

Insect protein has gradually attracted wide attention from the international research community as a promising source of high-quality protein that can replace traditional protein sources. The larvae of the housefly, a prevalent and widespread species, contain high levels of protein with beneficial properties, namely, anti-fatigue, anti-radiation, and anti-aging functions, as well as liver protection and immunity enhancement. This work thoroughly examined the impact of high-intensity ultrasound (HIUS) on the structural and functional characteristics of housefly larval concentrate protein (HLCP).

Effect of high hydrostatic pressure treatment on the antioxidant activity of lactoferrin before and after gastrointestinal digestion.

In this study, high hydrostatic pressure treatment of lactoferrin was used to investigate its effect on the hydrolysis and antioxidant activity of lactoferrin. The results showed that high hydrostatic pressure treatment at 600 MPa increased the exposure level of tryptophan residues of lactoferrin by 82.29%, which significantly altered the tertiary structure of lactoferrin, and this change was observed in scanning electron microscopy as an increase in the contact area of lactoferrin that could be contacted by proteases.

Integrating Transcriptomics and Metabolomics to Explore the Novel Pathway of Invading Colon Cancer Cells.

Colorectal cancer (CRC) is a malignancy with a very high incidence and mortality rate worldwide. bacteria and their metabolites play a role in inducing and promoting CRC; however, no studies on the exchange of information between extracellular vesicles (evs) and CRC cells have been reported. Our research shows that ATCC25586 secretes extracellular vesicles carrying active substances from parental bacteria which are endocytosed by colon cancer cells.

zz-1 Supplementation Mitigates Depression-Like Symptoms in Chronic Stress-Induced Depressed Mice via the Microbiota-Gut-Brain Axis.

Accumulating evidence has revealed an association between depression and disordered intestinal microecology. The discovery of psychobiotics has provided a promising perspective for studying the treatment of psychiatric disorders. Here, we aimed to investigate the antidepressant abilities of zz-1 (LRzz-1) and elucidate the underlying mechanisms.

Spatial distribution characteristics and prediction of fluorine concentration in groundwater based on driving factors analysis.

Excess fluoride (F) in groundwater can be hazardous to human health. A total of 360 ground water samples was collected from northern Anhui, China, to study the levels, distribution, and source of F. And on this basis, predicting the spatial distribution of F in a wider scale space.

zz-1 exerts preventive effects on chronic unpredictable mild stress-induced depression in mice regulating the intestinal microenvironment.

Depression remains one of the most prevalent psychiatric disorders, and it has been confirmed that it is related to the dysfunction of the microbiota-gut-brain axis. Manipulation of the gut microenvironment by probiotics might improve mental health and prevent stress-related psychiatric disorders. The present study aimed to determine whether () zz-1 could prevent the occurrence of depression and its potential mechanisms using a mouse model with chronic unpredictable mild stress (CUMS).

Task-irrelevant Auditory Event-related Potentials as Mental Workload Indicators: A Between-task Comparison Study.

Real-time monitoring of mental workload (MWL) is a crucial step to build closed-loop adaptive aiding systems for human-machine systems. MWL estimators based on spontaneous electroencephalography (EEG) and event-related potentials (ERPs) have shown great potentials to achieve this goal. However, the previous studies show that the between-task robustness of these EEG/ERP-based MWL estimators is still an unsolved intractable question.

[MicroRNA-29a-3p regulates osteoblast differentiation and peri-implant osseointegration in a rat model of hyperlipidemia by modulating Frizzled 4 expression].

Objective: This work aimed to study and identify the influence and target gene of microRNA-29a-3p (miR-29a-3p) in the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) in a high-fat environment in vitro and in vivo.

Methods: 1) In vitro: BMSCs were randomly allocated into two groups and were then induced to undergo osteogenic differentiation in a normal or high-fat environment. Next, a miR-29a-3p mimic/inhibitor was transfected into the two groups of cells.

MicroRNA-29a-3p enhances dental implant osseointegration of hyperlipidemic rats via suppressing dishevelled 2 and frizzled 4.

Background: Fine osseointegration is the basis of long-term survival of implant. In our previous study, we observed a strong correlation between hyperlipidemia and compromised osseointegration. MicroRNA-29a-3p (miR-29a-3p) has been discovered to participate in bone marrow mesenchymal stem cells (BMSCs) differentiation.