Effects of dissolved organic matter from different sources on ritonavir photolysis.

With the misuse of antiviral drugs, the residual levels of ritonavir (RTV) in aquatic environments continue to increase, potentially posing threats to ecosystems and human health. However, the current understanding of the photochemical behavior of RTV in water, especially the mechanism by which dissolved organic matter (DOM) from different sources affects the indirect photolysis of RTV, remains limited. This study systematically investigated the effects of DOM from different sources (including sludge, algae, dustfall, and soil, namely SL-DOM, AL-DOM, DF-DOM, and SO-DOM, respectively) on the photodegradation of RTV for the first time.

Resource requirements for essential universal health coverage: a modelling study based on findings from Disease Control Priorities, 3rd edition.

Background: Disease Control Priorities, 3rd edition (DCP3), published two model health benefits packages (HBPs). This study estimates the overall costs and individual component costs of these packages in low-income countries (LICs) and lower-middle-income countries (lower-MICs).

Methods: This study reports on our Disease Control Priorities Cost Model (DCP-CM), developed as part of the DCP3 project to determine the overall costs of the 218 health sector interventions recommended in the model HBP termed essential universal health coverage (EUHC).

Universal health coverage and intersectoral action for health: key messages from Disease Control Priorities, 3rd edition.

The World Bank is publishing nine volumes of Disease Control Priorities, 3rd edition (DCP3) between 2015 and 2018. Volume 9, Improving Health and Reducing Poverty, summarises the main messages from all the volumes and contains cross-cutting analyses. This Review draws on all nine volumes to convey conclusions.