Publications by authors named "Jinyu Wang"

The husk leaf of maize (Zea mays) encases the ear as a modified leaf and plays pivotal roles in protecting the ear from pathogen infection, translocating nutrition for grains and warranting grain yield. However, the natural genetic basis for variation in husk leaf width remains largely unexplored. Here, we performed a genome-wide association study for maize husk leaf width and identified a 3-bp InDel (insertion/deletion) in the coding region of the nitrate transporter gene ZmNRT2.

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Background: Osteosarcopenia is a geriatric syndrome associated with an increased risk of frailty, falls, fractures, disability, and death. Calf circumference (CC) has been used as a simple and practical skeletal muscle marker to diagnose sarcopenia. This study aimed to explore the relationship of calf circumference and osteoporosis (OP) and hip fractures (HF) in middle-aged and older adults.

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The persistent global burden of hepatitis B virus (HBV) infection has prompted ongoing investigations into host determinants of viral control. In this study, we investigate the regulatory influence of the host gene cleavage stimulation factor subunit 2 (CSTF2) on HBV replication dynamics. We demonstrate differential CSTF2 expression across the spectrum of HBV infection phases, with upregulated expression noted during the immune-reactive and inactive carrier states compared with the immune-tolerant phase.

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In recent years, various real-time processing methods have been developed for Satellite Laser Ranging (SLR) data. However, the recognition rate of the single-stage Graz filtering algorithm for high-orbit satellites is less than 1%, and traditional two-stage filtering algorithms, such as polynomial fitting and iterative filtering techniques, exhibit high false and missed detection rates. These issues compromise the accuracy of laser positioning and real-time adjustments during observations.

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Physical activity (PA) may be considered an alternative method to ameliorate the elevated mortality risks associated with cadmium exposure. In this prospective cohort study, a total of 20,253 participants (weighted mean age, 47.79 years), including 10,247 men (weighted prevalence: 50.

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  • * The study identified six key lactylation-related genes (LRGs) associated with IVDD progression, with CBX3 being the most significantly upregulated in experiments.
  • * Atosiban acetate was found to be a specific inhibitor of CBX3, effectively reducing glycolysis activity and lactylation levels, suggesting it could be a potential treatment for IVDD by targeting these biological processes.
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Undernutrition coexists with tuberculosis and is associated with adverse treatment outcomes. Nutrition packages have been incorporated into tuberculosis patient care in some regions but there are little data on its effectiveness. The aim of this study is to evaluate the effect of a nutrition package on the treatment response and nutritional status of tuberculosis patients.

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  • The study aimed to determine how clinical parameters and immunohistochemical markers can predict recurrence-free survival (RFS) in patients with early-onset endometrial cancer (EC) and to create a nomogram for accurate predictions.
  • The research included 458 patients for training and 170 for testing, using Cox regression models to identify key independent risk factors for RFS, ultimately developing a nomogram to forecast RFS at 3 and 5 years after surgery.
  • Key findings revealed that over half of the early-onset EC patients were aged 45-49, with a recurrence rate of about 10.8%, and identified independent factors such as histological subtype and FIGO stage, leading to the construction of a predictive nomogram
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  • Sulfate radical-based advanced oxidation technology using a functionalized NiAl-LDH@ceramic membrane (LDH@CM) shows promise for effectively removing organic pollutants from wastewater.
  • The LDH@CM demonstrates exceptional stability and a 100% catalytic performance in activating persulfate (PS) for pollutant degradation, aided by significant active species like O, ·OH, and SO·.
  • The engineered structure enhances mass transfer and maintains catalytic stability through mechanisms like oxygen vacancy promotion and confinement effects, presenting a new approach for practical wastewater treatment solutions.
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Background: Anterior controllable antedisplacement and fusion (ACAF) is an emerging surgical approach for treating cervical ossification of the posterior longitudinal ligament (C-OPLL), yet there is limited data on its long-term efficacy and safety. The present study aimed to analyze the short- and long-term postoperative clinical and radiological outcomes and perioperative complications of ACAF for patients with C-OPLL.

Methods: This was a single-center, retrospective, cohort study, with the mean duration of follow-up of at least 24 months.

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Polarization holography has emerged as a promising method for manipulating the amplitude, phase, and polarization states of light waves. This study proposes what we believe to be a novel design method for various all-optical logic devices, including a complete set of all-optical Boolean logic gates and a polarization-controlled 1 × 4 optical switch, utilizing polarization holography. Through the angle multiplexing technique, specially designed polarization holograms are recorded in polarization-sensitive material, transforming it into all-optical Boolean logic gates and a polarization-controlled 1 × 4 optical switch.

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Six iridium complexes were designed and studied using the DFT approach, (ppy)Ir(pic) (1), (fppy)Ir(pic) (2), (ppy)Ir(tmd) (3), (fppy)Ir(tmd) (4), (ppy)Ir(tpip) (5) and (fppy)Ir(tpip) (6). Here ppy denotes phenylpyridine, fppy denotes 2-(2,3,4,5-tetrafluorophenyl) pyridine, pic denotes benzoic acid, tmd denotes 5-hydroxy-2,2,6,6-tetramethylhept-4-en-3-one and tpip denotes tetraphenylimido-diphosphinate. The geometries, absorptions, emissions, frontier molecular orbitals, and spin-orbit coupling (SOC) constants of the 6 complexes were evaluated.

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Cervical cancer, often driven by high-risk human papillomavirus (HPV) infections such as HPV16 or HPV18, remains a leading cause of cancer-related deaths. HPV16, found in about 90% of cervical cancer patients, harbors key oncogenic related genes (E6, E7, E2, E5) and an upstream regulatory region (URR) that contribute to cancer progression. This study introduces a novel approach using a recombinant oncolytic herpes simplex virus type 1 (HSV-1) named SONC103, armed with a CRISPR/Cas9 gene editing system.

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  • The study evaluates the effects of the Fast Access to Surgery in Emergency (FASE) strategy on multidisciplinary team workflows and clinical outcomes for geriatric patients with femoral neck fractures (FNF).
  • A retrospective analysis of 344 patients highlighted that while the time in the emergency department increased under FASE, the time to surgery and overall hospital stay significantly decreased, along with improved blood management.
  • Despite these positive changes, the study found no significant differences in overall clinical outcomes, such as mortality rates or postoperative complications, between the FASE and control groups.
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High blood lipids, blood glucose, or blood pressure ("3Bs") are established risk factors for cardiovascular diseases. However, the effects of vegetarian diets on these parameters were inconsistent in previous meta-analyses. We conducted a systematic review and meta-analysis with comprehensive subgroup analyses, quality assessment, and sensitivity analyses to confirm the effects of vegetarian diets on 3Bs.

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SAR-to-optical (S2O) translation is able to covert SAR into optical images, which help the interpreter to extract information efficiently. In the absence of strictly matched datasets, it is difficult for existing methods to complete training on unpaired data with a minimum amount of data. By employing the recent Schrödinger bridge-based transformation framework, a multiscale axial residual module (MARM) based on the concept of multi-scale feature fusion has been proposed in this paper.

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  • Population mobility plays a crucial role in the spread of infectious diseases, affecting public health and sustainable development globally.
  • The study analyzed data from China between 2013 and 2019, discovering that intestinal diseases had the highest incidence, while sexually transmitted diseases had the highest mortality rate.
  • A strong correlation was found between passenger traffic (commercial and public) and various infectious diseases, highlighting transportation's impact on disease prevalence.
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The epigenetic process of RNA-directed DNA methylation (RdDM) regulates the expression of genes and transposons. However, little is known about the involvement of RdDM in the response of maize (Zea mays) to salt stress. Here, we isolated a salt-sensitive maize mutant and cloned the underlying gene, which encodes KOW DOMAIN-CONTAINING TRANSCRIPTION FACTOR1 (KTF1), an essential component of the RdDM pathway.

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Biochar prepared from crop straw is an economical method for adsorbing bromocresol green (BCG) from textile industrial wastewater. However, there is limited research on the adsorption mechanism of biochar for the removal of BCG. This study utilized cucumber straw as raw material to prepare biochar with good adsorption potential and characterized its physicochemical properties.

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Hypoxic pulmonary hypertension (HPH), a chronic condition affecting the cardiopulmonary system, has high mortality. Echinacoside (ECH) is a phenylethanoid glycoside, which is used to ameliorate pulmonary vascular remodeling and pulmonary vasoconstriction in rats. Accordingly, we aimed to explore the mechanism of ECH in preventing and treating HPH.

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  • Oncolytic virotherapy is a new cancer treatment strategy that uses modified viruses to trigger immune responses specifically against tumors, like the novel oncolytic virus (oHSV1-IL15B) developed from herpes simplex virus-1 (HSV-1) for colon cancer treatment.
  • In experiments with mice, oHSV1-IL15B demonstrated significant tumor-fighting effects, especially when combined with another oncolytic virus (oHSV-1-aPD1), resulting in better tumor inhibition and longer survival rates compared to using these treatments alone.
  • The study revealed that the combination therapies increased the presence of key immune cells (CD8 and CD4 T cells) and improved the tumor's immune environment, suggesting that combining
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  • - Research suggests that hypoxic pulmonary hypertension (HPH) activates the sympathetic nervous system, increasing norepinephrine (NE) release, which can lead to calcium overload and abnormal cell growth in pulmonary artery smooth muscle cells (PASMCs), contributing to vascular remodeling.
  • - The study examines how echinacoside (ECH) treatment affects these mechanisms, using NE-induced PASMCs to mimic the calcium overload and abnormal proliferation seen in HPH.
  • - Results show that ECH effectively reduces calcium levels and PASMC proliferation in a concentration-dependent manner, lowers the expression of certain proteins linked to this process, and significantly improves symptoms in HPH rat models by decreasing mean pulmonary artery pressure and alleviating pulmonary vascular remodeling.
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  • Duodenal motility disorder plays a role in causing dyspepsia, and the traditional Chinese medicine formula Wei-Tong-Xin (WTX) has shown effectiveness in relieving this condition.
  • The study aims to analyze the chemical composition of WTX and understand how it works to alleviate dyspepsia through a comprehensive approach including advanced analytical techniques and network pharmacology.
  • The research identified 100 chemical components in WTX, revealing that its therapeutic effects may involve regulating inflammation and oxidative stress, ultimately improving intestinal health and function in a mouse model of dyspepsia.
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