Nickel-catalyzed reductive cross-coupling of difluoromethylated secondary alkyl bromides with organohalides.

We present a highly efficient and versatile nickel-catalyzed protocol for the reductive cross-coupling of unactivated CFH-substituted electrophiles with a wide variety of aryl and alkenyl halides. This novel approach offers high catalytic reactivity and broad functional group compatibility, enabling late-stage fluoroalkylation of drug molecules.

Copper-catalyzed perfluoroalkylation of propargyl -dichlorides.

Herein, we present a highly efficient copper-catalyzed protocol for transforming propargyl -dichlorides into the corresponding chloro-substituted fluoroalkylated allenes. This protocol demonstrates a broad substrate scope and excellent tolerance towards various functional groups. Moreover, the strategy of utilizing the chloro-substituted pentafluoroethylation allenes for multiple transformations has shown significant value in synthetic chemistry.

The influence of storage conditions on the quality of fruits: A integrated investigation of constituent and antioxidant activity.

is a functional fruit with tonic effect and was widely used by traditional Chinese medicine for treatment and health care. The quality of fruit may vary by different storage condition. In this study, the influence of ambient temperature, humidity, packaging materials and period of storage on the quality of fruits were investigated.

Exploring the allelopathic autotoxicity mechanism of ginsenosides accumulation under ginseng decomposition based on integrated analysis of transcriptomics and metabolomics.

Continuous cropping obstacles seriously constrained the sustainable development of the ginseng industry. The allelopathic autotoxicity of ginsenosides is the key "trigger" of continuous cropping obstacles in ginseng. During harvest, the ginseng plants could be broken and remain in the soil.