Supplementary Far-Red Light for Photosynthetic Active Radiation Differentially Influences the Photochemical Efficiency and Biomass Accumulation in Greenhouse-Grown Lettuce.

Adding far-red (FR, 700-800 nm) light to photosynthetic active radiation (400-700 nm) proved to be a possible approach to increasing plant biomass accumulation for lettuce production in indoor vertical farms with artificial lighting as a sole-source lighting. However, how FR light addition influences plant growth, development, and metabolic processes and the optimal value of FR photon flux density for greenhouse-grown lettuce under sunlight are still unclear. This work aims to quantify the value of supplementary FR light with different intensities on lettuce morphological and physiological characteristics in a greenhouse.

Healthy Plasma Exosomes Exert Potential Neuroprotective Effects against Methylmalonic Acid-Induced Hippocampal Neuron Injury.

Exosomes have shown good potential for alleviating neurological deficits and delaying memory deterioration, but the neuroprotective effects of exosomes remain unknown. Methylmalonic acidemia is a metabolic disorder characterized by the accumulation of methylmalonic acid (MMA) in various tissues that inhibits neuronal survival and function, leading to accelerated neurological deterioration. Effective therapies to mitigate these symptoms are lacking.

Does social media usage contribute to cross-border social commerce? An empirical evidence from SEM and fsQCA analysis.

Drawing from the S-O-R perspective, this paper proposes a theoretical model explicating the mechanism whereby social media usage functions on customers' engagement in cross-cultural social commerce by employing a mixed-method approach including SEM and fsQCA analysis technique. Analysis of the data collected from 135 countries' 2058 international students indicates that social media usage, either for information or socializing purpose, exerts positive effects on international customers' engagement in social commerce through the conduit of cultural identity change, and social support positively moderates the relationships between two dimensions of social media usage and cultural identity change. The analysis of fsQCA further augmented the robust results reached from SEM and identified four types of configurations that trigger customers' engagement in cross-border social commerce.

Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion.

Ischemic accumulation of succinate causes cerebral damage by excess production of reactive oxygen species. However, it is unknown whether ischemic accumulation of succinate affects neural stem cell proliferation. In this study, we established a rat model of cerebral ischemia/reperfusion injury by occlusion of the middle cerebral artery.

Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway.

Plant exosome-like nanoparticles (ELNs) have shown great potential in treating tumor and inflammatory diseases, but the neuroprotective effect of plant ELNs remains unknown. In the present study, we isolated and characterized novel ELNs from (MC) and investigated their neuroprotective effects against cerebral ischemia-reperfusion injury. In the present study, MC-ELNs were isolated by ultracentrifugation and characterized.

Healthy Serum-Derived Exosomes Improve Neurological Outcomes and Protect Blood-Brain Barrier by Inhibiting Endothelial Cell Apoptosis and Reversing Autophagy-Mediated Tight Junction Protein Reduction in Rat Stroke Model.

Blood-brain barrier (BBB) dysfunction causing edema and hemorrhagic transformation is one of the pathophysiological characteristics of stroke. Protection of BBB integrity has shown great potential in improving stroke outcome. Here, we assessed the efficacy of exosomes extracted from healthy rat serum in protection against ischemic stroke and .