Tongue crack recognition using segmentation based deep learning.

Tongue cracks refer to fissures with different depth and shapes on the tongue's surface, which can characterize the pathological characteristics of spleen and stomach. Tongue cracks are of great significance to the objective study of tongue diagnosis. However, tongue cracks are small and complex, existing methods are difficult to extract them effectively.

Synthesis of Phenylboronic Acid-Functionalized Magnetic Nanoparticles for Sensitive Soil Enzyme Assays.

Soil enzymes, such as invertase, urease, acidic phosphatase and catalase, play critical roles in soil biochemical reactions and are involved in soil fertility. However, it remains a great challenge to efficiently concentrate soil enzymes and sensitively assess enzyme activity. In this study, we synthesized phenylboronic acid-functionalized magnetic nanoparticles to rapidly capture soil enzymes for sensitive soil enzyme assays.

Population based and animal study on the effects of Schistosoma japonicum infection in the regulation of host glucose homeostasis.

Although parasitic infection affects the glucose homeostasis of mice, only few studies have integrated epidemiological and animal data to determine the effect of Schistosoma japonicum infection on mice metabolism. The current study assessed the effects of S. japonicum infection on blood glucose and other metabolic parameters in both patients and animal models of chronic schistomiasis.

BET bromodomain is a novel regulator of TAZ and its activity.

Transcriptional coactivator with PDZ-binding motif (TAZ) is a key transcriptional mediator of Hippo signaling that has been recently reported to mediate Wnt-activated transcription and serve as a component to suppress canonical Wnt/β-catenin activity. The Bromodomain and Extra-terminal domain (BET) family of proteins can recognize the acetylated lysine chain on histones and plays a critical role in transcriptional regulation. However, the mechanisms underlying transcriptional repression by the BET bromodomain are poorly understood.

Extensive metabolic disorders are present in APC(min) tumorigenesis mice.

Wnt signaling plays essential role in mesenchymal stem cell (MSC) differentiation. Activation of Wnt signaling suppresses adipogenesis, but promotes osteogenesis in MSC. Adenomatous polyposis coli (APC) is a negative regulator of β-catenin and Wnt signaling activity.

Super enhancers at the miR-146a and miR-155 genes contribute to self-regulation of inflammation.

Inflammatory response is essential to host defense and repair, and requires tight regulation as excessive and constant inflammatory response is deleterious. We recently identified that one of the general but key mechanisms for inflammatory gene transcription regulation is controlled by the formation of super enhancers mediated by NF-κB, and bromodomain and extraterminal (BET) proteins. Given that microRNA transcription shares a similar mechanism to mRNA, we assume that the inflammatory microRNAs transcription could be NF-κB and BET bromodomain dependent.

Spectral efficiency limits of pre-filtered modulation formats.

We investigate the spectral efficiency (SE) limit of pre-filtered modulation in optical fiber communication systems. We show that pre-filtering induced symbol correlation generates a modulation with memory and, thus, a higher SE limit than that of the original memoryless modulation. The SE limits of a series of modulation formats with varying number L of correlated symbols producing 50% of the original bandwidth are evaluated, which approach the SE limit of a modulation format with 50% pre-filtering as L --> ∞.