Identification of predictors and construction of a prediction model for the quality of life in laryngeal carcinoma patients in China using revised core nursing outcomes.

Background: This study aimed to identify potential predictors and construct a predictive model for the quality of life (QoL) in patients with laryngeal carcinoma (LC) using the revised core nursing outcomes.

Methods: We recruited 331 LC patients underwent laryngectomy between March 2018 and March 2022 from three hospitals. The revised core nursing outcomes contained 14 items in the "Physiologic Health," "Psychosocial Health," "Health Knowledge & Behavior," and "Perceived Health", while the QoL was assessed using the Chinese version of the Functional Assessment of Cancer Therapy-Head and Neck.

Endoscopic Surgery for a Case of Congenital Cholesteatoma with Ossicular Chain Anomaly.

The simultaneous occurrence of congenital ossicular anomalies and congenital cholesteatoma (CC) is exceedingly rare. This report describes the case of an 11-year-old boy who presented with conductive hearing loss, characterized by an average air conduction threshold of 50 dB in the left ear, without any prior otologic history. Preoperative assessments suggested the presence of CC, with suspicion of ossicular chain malformation.

Preparation of altrenogest soft capsules and their bioequivalence in gilts.

Introduction: Altrenogest (ALT) is widely used to regulate the estrous cycle of sows and mares; however, currently used oral solutions of ALT are deficient in terms of dose accuracy and stability during use. To resolve these problems, we aimed to prepare softgel capsules of ALT with a unit dose equal to the clinically administered dose.

Method: The shell of the softgel capsule was mainly composed of gelatin and glycerol, with titanium dioxide and red iron oxide as masking agents.

Microencapsulated essential oils alleviate diarrhea in weaned piglets by modulating the intestinal microbial barrier as well as not inducing antibiotic resistance: a field research.

Microencapsulated essential oils (MEO)have been used as antibiotic alternatives that can be applied to alleviate diarrhea in weaning piglet. We examined a large group of weaned piglets and incorporated essential oil containing thymol (2%), carvacrol (5%) and cinnamaldehyde (3%) in the feed of weaned piglets on an intensive production farm. The piglets were divided into four groups; Control (no additions) and chlortetracycline (Chl), essential oil (EO) and microencapsulated essential oil (MEO) were fed over a 28-day trial period.

Sensitivity-Enhanced, Room-Temperature Detection of NH with Alkalized TiCT MXene.

A layered TiCT MXene structure was prepared by etching MAX-phase TiAlC with hydro-fluoric acid (HF), followed by alkalization in sodium hydroxide (NaOH) solutions of varying concentrations and for varying durations. Compared to sensors utilizing unalkalized TiCT, those employing alkalized TiCT MXene exhibited enhanced sensitivity for NH detection at room temperature and a relative humidity of 40%. Both the concentration of NaOH and duration of alkalization significantly influenced sensor performance.

Molecular mechanism of bovine Gasdermin D-mediated pyroptosis.

Pyroptosis is a form of programmed cell death characterized by cell swelling, pore formation in the plasma membrane, lysis, and releases of cytoplasmic contents. To date, the molecular mechanism of human and murine Gasdermin D-mediated pyroptosis have been fully investigated. However, studies focusing on molecular mechanism of bovine Gasdermin D (bGSDMD)-mediated pyroptosis and its function against pathogenic infection were unclear.

Mycobacterial PE12 protein promotes bacterial survival through inhibiting cell apoptosis.

Mycobacterial PE_PGRS family proteins play key roles in pathogen-host interaction. However, the function of most PE_PGRS proteins remains unknown. In this study, we characterized the role of PE12 of Mycobacterium bovis (M.

Serum cell division cycle 42 in advanced hepatocellular carcinoma patients: Linkage with clinical characteristics and immune checkpoint inhibitor-related treatment outcomes.

Objective: Cell division cycle 42 (CDC42) facilitates immune escape and drug resistance towards immunotherapy in several malignancies. This prospective study aimed to explore the predictive value of serum CDC42 for immune checkpoint inhibitor (ICI)-treatment response and survival in advanced hepatocellular carcinoma (HCC) patients.

Methods: Thirty advanced HCC patients scheduled for ICI or ICI-based treatment were enrolled in this prospective study, whose serum CDC42 was determined via enzyme-linked immunosorbent assay before therapy initiation.

The predictive model for COVID-19 pandemic plastic pollution by using deep learning method.

Pandemic plastics (e.g., masks, gloves, aprons, and sanitizer bottles) are global consequences of COVID-19 pandemic-infected waste, which has increased significantly throughout the world.

Carbon dots modified/prepared by supramolecular host molecules and their potential applications: A review.

Supramolecular host molecules are used as tools in the design of multifunctional nanoparticles for sensors, catalysts, biometric elements, etc. Combining with carbon dots (CDs) has excellent host-guest recognition properties and fluorescence characteristics, which can precisely capture and identify target analytes. Consequently, supramolecular host molecules-based CDs can significantly improve the detection performance of ions and molecules with different structures or intrinsic chemical properties.

Tenofovir alafenamide in blocking mother-to-child transmission of hepatitis B virus: a multi-center, prospective study.

Background: Data of tenofovir alafenamide (TAF) in preventing mother-to-child transmission (MTCT) of hepatitis B virus (HBV) are limited. This study aimed to evaluate the effectiveness and safety of TAF for preventing MTCT.

Methods: Pregnant women with chronic HBV infection, positive for HBeAg and high-level HBV DNA, received oral TAF from gestational weeks 24-28 until postpartum week 4.

Nurse-led telephone follow-up according to the revised nursing outcomes classification for laryngeal carcinoma surgery patients: a randomized controlled trial.

Background: This study used the revised nursing outcomes classification (NOC) outlined in our previous study, "Core nursing outcomes for otorhinolaryngology head-neck," for telephone follow-up of patients who had laryngeal carcinoma surgery in China. This randomized controlled trial aimed to compare nurse-led telephone follow-up according to the revised NOC with traditional telephone follow-up.

Methods: A total of 100 postoperative patients were recruited from March 2018‒March 2020.

Sensing performance and mechanism of carbon dots encapsulated into metal-organic frameworks.

Metal-organic frameworks (MOFs) can be combined with nanomaterials and the combined composites have excellent optical properties. Carbon dots (CDs) with tiny particle size, non-toxic and rich surface functional groups are novel fluorescent materials. Carbon dots@metal-organic frameworks (CDs@MOFs) are synthesized by encapsulating CDs into MOFs.

Carbon dots as a promising therapeutic approach for combating cancer.

With advances in nanotechnology and the development of emerging therapeutic modalities, a surge in research on the use of nanomedicines for biomedical applications has occurred over the past three decades. Carbon dots (CDs) are new members of carbon-based nanomaterials that can be used in cancer treatment to reduce side effects of drugs and improve treatment efficiency, offering new medical opportunities for further research. Urged as such, we are encouraged to classify CDs-based cancer treatments, including photodynamic therapy (PDT), photothermal therapy (PTT), sonodynamic therapy (SDT), chemodynamic therapy (CDT), chemotherapy (CT), and synergistic therapy.

Value of serum miR-21, HE4 and CA125 in surveillance for postoperative recurrent or metastatic ovarian cancer.

Objectives: To study the value of serum miR21, human epididymal secretory protein 4 (HE4) and carbohydrate antigen 125 (CA125) in the surveillance for postoperative recurrent or metastatic ovarian cancer.

Methods: A total of 169 patients diagnosed with ovarian conditions in Luanzhou Hospital of Traditional Chinese Medicine during January 2016 and March 2019 were divided into a benign lesion (BL) group and an ovarian cancer (OC) group by pathological findings and assigned to a good prognosis (GP) group and a poor prognosis (PP) group according to the follow-up results. A real-time fluorescence quantitative PCR (RT-fqPCR) system was utilized to detect the serum level of miR-21; an enzyme-linked immunosorbent assay (ELISA) was conducted to determine the serum level of HE4; electrochemiluminescence (ECL)-based imaging analysis was performed to measure serum CA125.

Neoadjuvant pyrotinib plus nab-paclitaxel, doxorubicin, and cyclophosphamide for HER2-positive locally advanced breast cancer: a retrospective case-series study.

Background: The anti-tumor activity of pyrotinib has been confirmed in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer. This study investigated the effect of pyrotinib plus nab-paclitaxel, doxorubicin, and cyclophosphamide as neoadjuvant therapy in patients with HER2-positive locally advanced breast cancer.

Methods: In this single-center retrospective study, female patients with HER2-positive locally advanced breast cancer received pyrotinib 320 mg orally once a day and the TAC regimen (nab-paclitaxel 260 mg/m, liposomal doxorubicin 20 mg/m, and cyclophosphamide 600 mg/m) on day 1 of each 21-day cycle.

The negative impact of increasing temperatures on rice yields in southern China.

China is the main producer and consumer of rice in the world, and rice is a major staple food grain for more than half of the world's population. Reduced rice yields caused by climate factors not only affect the food security of China, but also has global repercussions. Thus, it is vital to assess the potential impact of climate warming on rice production.

Intelligent Recognition Algorithm-Based Color Doppler Ultrasound in the Treatment of Dangerous Placenta Previa.

The study focused on the clinical diagnostic value of color Doppler ultrasound of dangerous placenta previa patients under the guidance of intelligent recognition algorithms. 58 patients with placenta previa and placenta accreta admitted to the hospital for treatment were selected as research subjects. The color Doppler ultrasound under the guidance of intelligent recognition algorithm was compared with the two-dimensional ultrasound for specificity, sensitivity, and accuracy.

Self-quenching-resistant solid-state carbon dots for mechanism and applications.

Solid-state carbon dots (SCDs) have been widely investigated by scholars owing to their stability, environmental friendliness, and their good optical properties. The current studies on carbon dots (CDs) are mainly focused on the solutions of CDs, while the researches on SCDs are relatively few in comparison. Nowadays, the fabrication and design of high-performance SCDs have attracted much interest.

Evaluation and revision of core postoperative nursing outcomes for laryngeal carcinoma in China.

Background: The core nursing outcomes for laryngeal carcinoma in China needed further screening and revision. This study aimed to evaluate and revise a questionnaire according to the "Core Nursing Outcomes for Otorhinolaryngology Head-Neck" of the Nursing Outcomes Classification (NOC, 5th Edition), and determine suitable postoperative nursing outcomes for patients with laryngeal carcinoma in China.

Methods: The commonly used postoperative nursing outcomes for laryngeal carcinoma were screened using a questionnaire given to 93 nurses.

WITHDRAWN: Effect of abdominal aortic balloon occlusion timing on femoral nerve injury in patients with dangerous placenta preview based on color dropper ultrasound images.

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found athttps://www.

Effects of PEDOT:PSS:GO composite hole transport layer on the luminescence of perovskite light-emitting diodes.

Perovskite light-emitting diodes (PeLEDs) employing CHNHPbBr as the emission layer (EML) and graphene oxide (GO) doped PEDOT:PSS as the hole transport layer (HTL) were prepared and characterized. GO doped in PEDOT:PSS can lead to the increased work function of HTL and lower the hole injection barrier at the HTL/CHNHPbBr interface, which facilitates the hole injection. Meanwhile, the optimized GO amount in PEDOT:PSS can help to reduce the quenching of luminescence occurring at the interface between HTL and perovskite.

WS quantum dots-MnO nanosheet system for use in ratiometric fluorometric/scattered light detection of glutathione.

Based on WS quantum dots (QDs) as fluorescent signals and MnO nanosheets as second-order scattering (SOS) signals, a combination of fluorescence and scattered light was used to construct a ratio sensing platform for glutathione (GSH) detection. When MnO nanosheets are added to WS QDs, the fluorescence of WS QDs is quenched by MnO nanosheets through IFE. Large-sized MnO nanosheets increase the SOS of the system and gradually approach the fluorescence.

Enhanced performance of InO nanowire field effect transistors with controllable surface functionalization of Ag nanoparticles.

Indium oxide (InO) nanowire field effect transistors (FETs) have great potential in electronic and sensor applications owing to their suitable band width and high electron mobility. However, the InO nanowire FETs reported previously were operated in a depletion-mode, not suitable to the integrated circuits result of the high-power consumption. Therefore, tuning the electrical properties of InO nanowire FETs into enhancement-mode is critical for the successful application in the fields of high-performance electronics, optoelectronics and detectors.

Impacts of Drought on Maize and Soybean Production in Northeast China During the Past Five Decades.

Climate change has a distinct impact on agriculture in China, particularly in the northeast, a key agriculture area sensitive to extreme hydroclimate events. Using monthly climate and agriculture data, the influence of drought on maize and soybean yields-two of the main crops in the region-in northeast China since 1961 to 2017 were investigated. The results showed that the temperature in the growing season increased by 1.