Publications by authors named "Jinxi Lan"
Article Synopsis
- A diabetic wound healing is complicated by high blood sugar, nerve damage, and blood vessel issues, which can lead to infections and slow healing.
- Researchers developed a new wound dressing that not only fights bacteria but also helps create new blood vessels (angiogenesis) while lowering glucose levels at the wound site.
- This dressing combines a special copper-based compound with enzymes to generate antibacterial agents and promote healing, demonstrating significant potential for improving the treatment of chronic wounds in diabetic patients.
A novel bola-molecular self-assembling hydrogel for enhancing diabetic wound healing.
J Colloid Interface Sci
April 2024
Hypothesis: Chronic wounds, particularly those caused by diabetes, pose a significant challenge for clinical treatment due to their prolonged healing process and associated complications, which can lead to increased morbidity. A biocompatible hydrogel with strong antibacterial properties and the ability to promote angiogenesis can be directly absorbed in the wound site for healing.
Experiments: A series of self-healing, antibacterial bolaamphiphilic supramolecular self-assembling hydrogels (HLQMes/Cu) were developed based on metal-ligand coordination between various concentrations of Cu solution and the head group of l-histidine methyl ester in HLQMes.