Steroidal saponins from the roots of Paris verticillata and their anti-proliferative and anti-inflammatory activities.

Thirteen previously undescribed steroidal saponins, named parisverticilloside A-M (1-13) and twenty known steroidal saponins (14-33) were isolated from ethanol extract of the roots of Paris verticillata. Their structures were identified by a series of spectroscopic methods, including 1D and 2D NMR, HR-ESI-MS, optical rotatory dispersion and chemical processes. The anti-proliferative activities of all compounds against LN229, HepG2, MDA-MB-231 and 4T1 cell lines were evaluated using the CCK8 assay with cisplatin or capecitabine as the positive control.

Mechanical Properties and Uniaxial Failure Behavior of Concrete with Different Solid Waste Coarse Aggregates.

To reveal the differences between the mechanical properties of solid waste coarse aggregate concrete and natural coarse aggregate concrete (NCAC) under equal strength, the basic mechanical properties of coarse aggregate concrete with seven different solid wastes (i.e., self-combusted coal gangue, uncombusted coal gangue, marble sheet waste, granite sheet waste, iron waste rock, recycled concrete, and self-combusted coal gangue ceramicite) were tested, and the trends in failure morphology, elastic modulus, and the stress-strain full curves of the different solid waste coarse aggregate concretes were analyzed and compared with NCAC.

Two new quinic acid derivatives from the leaves of .

Two new () and three known quinic acid derivatives () were isolated from the leaves of (Turcz) Baill. The structures of the compounds were determined by spectroscopic methods, especially the NMR techniques, and also by comparison with reported data in the literature. The cytotoxicity activities of these compounds were evaluated on human tumor cell lines LN229 and three of them showed a certain activity.