Genomic characterisation of the Jk(a-b-) phenotype in Thai blood donors.

Background: The Kidd (JK) blood group antigens are encoded by the JK gene. The rare Jk(a-b-) phenotype can be caused by homozygosity for a silent JK allele. Currently, JK(null) alleles have been identified among different populations; however, information on its presence among Thais is not available.

Antibody elutions in Thai patients with a positive direct antiglobulin test.

Background: The direct antiglobulin test is performed to determine whether an anaemic patient with evidence of haemolysis has autoimmune or alloimmune haemolytic anaemia.

Materials And Methods: We determined the antibody specificity of eluted IgG antibodies from patients' blood samples with a positive direct antiglobulin test. Overall, 134 Thai patients were included in this study.

Jk(a-b-) phenotype screening by the urea lysis test in Thai blood donors.

Background: The Jk(a-b-) phenotype is rare in most populations and often detected after transfusion or pregnancy. After immunisation, anti-Jk3 forms and it can be difficult to find compatible Jk(a-b-) donors. Using anti-Jk(a) and anti-Jk(b) in a conventional tube method is unsuitable for identifying Jk(a-b-) in mass screening of blood donors.