Publications by authors named "Jinshui Chang"

Article Synopsis
  • - Retained fetal membranes (RFM) in dairy cows is a reproductive condition related to the adhesion of placenta tissue, significantly involving collagen type IV (COL-IV) breakdown, crucial for placental expulsion.
  • - The study aimed to explore the role of the focal adhesion kinase (FAK) signaling pathway in regulating COL-IV, with tissue samples collected from healthy cows and those with RFM for comparison.
  • - Results showed that in RFM cows, levels of key FAK pathway proteins (FAK, Src, MMP-2, and MMP-9) were lower while COL-IV levels were higher, indicating a potential pathway disruption related to RFM that could influence future treatment strategies.
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Clinical ketosis is a detrimental metabolic disease in dairy cows, often accompanied by severe lipolysis and inflammation in adipose tissue. Our previous study suggested a 2.401-fold upregulation in the calmodulin (CaM) level in the adipose tissue of cows with clinical ketosis.

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Article Synopsis
  • * The study compared normal cows with adequate vitamin E levels and those deficient in vitamin E, revealing that VED cows had poorer body condition scores, lower milk production, and less feed intake.
  • * Metabolic profiling showed VED cows exhibited significant changes in 24 metabolites, impacting various metabolic pathways, including energy and amino acid metabolism, indicating a broad metabolic disruption due to vitamin E deficiency.
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