(AMK) as an oriental medicine has been used in the treatment of threatened abortion. (AT-I) is one of the major bioactive components of AMK. This study aimed to investigate the effect of AT-I on the secretion of estradiol (E) and progesterone (P) in feline ovarian granulosa cells (FOGCs), which is necessary for pregnancy.
View Article and Find Full Text PDFIt is proven through transmission electron microscope (TEM) analysis that solar sensitizer CuSnS (CTS) dots prepared via the hot-injection route are nonspherical, polyhedral nanocrystals with the size of ∼11 nm. CTS dots were deposited into a porous TiO layer to form CTS/TiO, an effective type II heterojunction in photoanodes. The electronic and energy band structures of TiO and CTS were studied by the plane-wave ultrasoft pseudopotential method based on density functional theory (DFT) and verified by ultraviolet-visible (UV-vis) spectroscopy.
View Article and Find Full Text PDFAnal swabs of 1-month-old Holstein calves with diarrhea were collected from an intensive cattle farm, and a highly pathogenic Escherichia coli strain was obtained by isolation and purification. To study the virulence and resistance genes of pathogenic E. coli that cause diarrhea in calves, a strain of E.
View Article and Find Full Text PDFDifferent antibiotics are used to treat mastitis in dairy cows that is caused by Antimicrobial resistance in food-producing animals in China has been monitored since 2000. Surveillance data have shown that the prevalence of multiresistant in animals has increased significantly. This study aimed to investigate the occurrence and molecular characteristics of resistance determinants in strains ( = 105) obtained from lactating cows with clinical bovine mastitis (CBM) in China.
View Article and Find Full Text PDFStaphylococcus aureus (S. aureus) is one of the most infamous and widespread bacterial pathogens, causing a hard-to-estimate number of uncomplicated skin infections and probably hundreds of thousands to millions of more severe, invasive infections globally per year. S.
View Article and Find Full Text PDFS. aureus isolated from bacterial bovine endometritis is common in epidemiological reports, but is often ignored as a subclinical pathogenic microorganism. In a previous study, we showed that live S.
View Article and Find Full Text PDFProstaglandins Other Lipid Mediat
December 2023
Prostaglandin D (PGD) synthesis is closely associated with the innate immune response mediated by pattern recognition receptors (PPRs). We determined PGD synthesis whether mediated by Toll-like receptor 2 (TLR2), TLR4 and Nod-like receptor pyrin domain-containing protein 3 (NLRP3) in Escherichia coli (E. coli)-, lipopolysaccharide (LPS)- and Braun lipoprotein (BLP)-stimulated macrophages.
View Article and Find Full Text PDFIntroduction: In clinical settings, dairy cows are often attacked by pathogenic bacteria after delivery, especially (). Neutrophils have long been regarded as essential for host defense against . Prostaglandin E (PGE) can additionally be used as an inflammatory mediator in pathological conditions to promote the repair of inflammatory injuries.
View Article and Find Full Text PDFDairy cows often develop different degrees of endometritis after calving and this is attributed to pathogenic bacterial infections such as by Escherichia coli and Staphylococcus aureus. Infection of the bovine endometrium causes tissue damage and increases the expression of prostaglandin D (PGD), which exerts anti-inflammatory effects on lung inflammation. However, the roles of PGD and its DP1 receptor in endometritis in cows remain unclear.
View Article and Find Full Text PDFWhen some sub-images lack ground control points (GCPs) or GCPs are not evenly distributed, the estimated camera parameters are often deviated in in-orbit geometric calibration. In this study, a feasible in-orbit geometric calibration method for multi-linear array optical remote sensing satellites with tie constraints is presented. In the presented method, both GCPs and tie points are employed.
View Article and Find Full Text PDFProstaglandin E (PGE ) is able to induce the expression of several growth factors and enzymes in cattle endometria. However, the specific type of PGE receptors which mediates this effect is not fully clear. In this study, the role of prostaglandin E receptor 2 (PTGER2) in PGE -mediated induction of growth factors and enzymes expression in cattle endometrial explants and epithelial cells were investigated.
View Article and Find Full Text PDFAcute lung injury (ALI) is an inflammatory lung disease that is caused by bacterial infection. Lipopolysaccharide (LPS), a prototype pathogen-associated molecular pattern (PAMP) from Gram-negative bacteria such as (), is an essential risk factor for ALI. LPS and induced the activation of mitogen-activated protein kinase (MAPK) and nuclear factor kappaB (NF-κB) signaling pathways, which led to the increasing immune molecule transcription, including pro-inflammatory cytokine and chemokine secretion.
View Article and Find Full Text PDFProstaglandins Leukot Essent Fatty Acids
November 2021
It is known that prostaglandin E (PGE) induces proliferation of epithelia in bovine endometrial explants, however, the detailed mechanism of regulation of PGE in inducing bovine endometrial epithelial cell (bEEC) proliferation is unclear. In this study, we determined whether proliferation of bEECs is promoted by PGE-prostaglandin E receptor 2 (PTGER2) signaling activation through cell cycle regulation. The results demonstrated that bEECs proliferation was induced by treatment of PGE and PTGER2 agonist butaprost.
View Article and Find Full Text PDFBiomed Res Int
July 2021
This article is aimed at analyzing the structure and function of the spike (S) proteins of porcine enteric coronaviruses, including transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome coronavirus (SADS-CoV) by applying bioinformatics methods. The physical and chemical properties, hydrophilicity and hydrophobicity, transmembrane region, signal peptide, phosphorylation and glycosylation sites, epitope, functional domains, and motifs of S proteins of porcine enteric coronaviruses were predicted and analyzed through online software. The results showed that S proteins of TGEV, PEDV, SADS-CoV, and PDCoV all contained transmembrane regions and signal peptide.
View Article and Find Full Text PDFThe HaiYang-1C coastal zone imager (CZI) consists of two independent cameras with a total image swath of approximately 1000 km. In order to obtain precise imaging parameters of the CZI cameras, a feasible in-orbit geometric calibration approach with multiple fields is presented. First, the master CCD is calibrated with a calibration field.
View Article and Find Full Text PDFProstaglandin E2 (PGE) enhances Staphylococcus aureus infection but its mechanism is not well understood. Here, we examined the effect of PGE on Staphylococcal Protein A (SPA) expression in bovine endometrium and determined the role of select PGE receptors (i.e.
View Article and Find Full Text PDFProstaglandins Leukot Essent Fatty Acids
May 2021
Bovine endometrium infection with gram-negative bacteria commonly causes uterine diseases. Previous studies indicate that prostaglandin E (PGE) is an inflammatory mediator in bacterial endometritis. However, the mechanism underlying lipopolysaccharide (LPS)-induced inflammatory response regulation in bovine endometrial explants remains elusive.
View Article and Find Full Text PDFBovine endometritis is one of the major postpartum diseases associated with infertility and subfertility, decreasing the benefit of dairy industry. It is important to develop alternate therapies for endometritis in the context of drug residues in the milk and hormone disorder in the estrous cycle. α7 nicotine acetylcholine receptor has been identified as the core of 'cholinergic anti-inflammatory pathway (CAP)', which is a potential drug target to inflammatory diseases.
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