Publications by authors named "Jinru Zhu"
Obstructive sleep apnea (OSA) often leads to complications in the elderly. This study compares the usefulness of five screening tools for OSA in elderly patients. Data from elderly patients diagnosed with OSA, collected from the Sleep Medicine Center of the First Affiliated Hospital of Guangzhou Medical University from January 2012 to June 2017, is analyzed.
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- * The analysis shows no significant impact of bevacizumab on the duration of epistaxis or the frequency of episodes compared to the control group.
- * There are no notable differences in adverse effects between the bevacizumab and control groups, indicating it has clinical value in treating HHT epistaxis without increasing side effects.
Objective: This study seeks to systematically evaluate and test the effects of yoga exercise intervention programs on sleep quality in breast cancer patients in order to suggest more optimized exercise programs.
Method: Computer searches of the PubMed, Embase, Cochrane Library, Web of Science and CINAHL databases are conducted from the date of their inception to June 8, 2022 to collect randomized controlled trials on the effects of yoga exercise intervention on sleep quality in breast cancer patients. Two investigators independently carry out the inclusion and exclusion criteria literature screening, data extraction and methodological quality assessment of the included literature by applying the Cochrane risk of bias tool.
Article Synopsis
- - The study aimed to investigate the relationship between sleep duration and the risk of developing type II diabetes in adults by analyzing multiple databases and literature up to October 2022.
- - A meta-analysis of 5 studies involving 74,226 subjects found that women with long sleep duration (LSD) have a significantly higher risk of type II diabetes compared to men, while men with short sleep duration (SSD) show a trend towards higher risk that isn't statistically significant.
- - The findings suggest that women with LSD are at greater risk for type II diabetes, and that men in Europe and America with SSD are also at an increased risk compared to men from other regions.
Some ceRNA associated with lncRNA have been considered as possible diagnostic and therapeutic biomarkers for obstructive sleep apnea (OSA). We intend to identify the potential hub genes for the development of OSA, which will provide a foundation for the study of the molecular mechanism underlying OSA and for the diagnosis and treatment of OSA. We collected plasma samples from OSA patients and healthy controls for the detection of ceRNA using a chip.
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- This study examines how obstructive sleep apnea-hypopnea syndrome (OSAHS) is linked to osteoporosis, focusing on its effects on the incidence of the disease and bone mineral density (BMD) in the lumbar spine.
- A systematic search of multiple databases identified 15 articles involving over 113,000 subjects, revealing that people with OSAHS have a significantly higher incidence of osteoporosis and lower lumbar spine BMD and T-scores compared to a control group.
- The study concludes that increased awareness and management of OSAHS is essential to lower the risk of osteoporosis, emphasizing the need for active sleep intervention strategies.
Article Synopsis
- Obstructive sleep apnea (OSA) is common and serious, and this study evaluates the GOAL questionnaire’s effectiveness as a screening tool compared to others like NoSAS and STOP-Bang.
- Data from over 2,000 patients showed that the GOAL questionnaire has a high sensitivity (89.1%) and comparable area under the curve (AUC) scores to other tools, particularly when the apnea hypopnea index (AHI) threshold is set at 5 events/hour.
- The study concludes that GOAL is a free and efficient tool for screening OSA, performing better than some existing questionnaires in terms of identifying patients.
Objective: This study seeks to investigate the relationship between Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) and hearing impairment by meta-analysis.
Methods: Cochrane Library, PubMed, Embase, Web of Science and other databases are searched from their establishment to July 1st, 2022. Literature on the relationship between OSAHS and hearing loss is collected, and two researchers independently perform screening, data extraction and quality evaluation on the included literature.
Objective: The purpose of this meta-analysis is to systematically assess the effects of psychological intervention on empathy fatigue among nursing staff.
Method: Five electronic databases are searched separately from their establishment to April 8th, 2022. The research team independently performs paper selection, quality assessment, data extraction and analysis for all included studies.
Article Synopsis
- This study investigates the effectiveness of using the STOP-Bang questionnaire alongside the Epworth Sleepiness Scale (ESS) for detecting obstructive sleep apnea (OSA) in a patient population.
- Data from 1,671 patients suspected of having OSA were analyzed through overnight polysomnography, revealing the diagnostic strengths and weaknesses of both screening tools.
- The findings suggest that using a STOP-Bang score of ≥3 in combination with ESS enhances the screening’s specificity for OSA diagnosis and recommends further evaluation of patients with this score.
A meta-analysis is used to explore the relationship between polycystic ovary syndrome (PCOS) and the risk of Sleep disturbances. Cochrane Library, PubMed, Embase, and Web of Science databases are searched by computer from their establishment to 1 May 2022. Review Manager 5.
View Article and Find Full Text PDFMeta-Analysis of Relationship of Sleep Quality and Duration With Risk of Diabetic Retinopathy.
Front Endocrinol (Lausanne)
July 2022
Objective: A meta-analysis is used to explore the relationship of sleep quality and duration with the risk of diabetic retinopathy (DR).
Method: Cochrane Library, PubMed, Embase, and other databases are searched from their establishment to April 2022. Literature on the relationship of sleep quality and duration with DR risk published in various databases is collected, and two researchers independently screen the literature, extract data, and evaluate the quality of the included articles.
Background: The role of adenylate cyclase 7 (ADCY7) in cancer is still unclear. This study analyzed the interrelationship between the expression and immune function of ADCY7.
Methods: ADCY7 expression in multiple human cancers was analyzed using the databases of Genotype-Tissue Expression Project (GTEx), Cancer Cell Line Encyclopedia (CCLE), and The Cancer Genome Atlas (TCGA).
This study aimed to screen key biomarkers and investigate immune infiltration in pulmonary arterial hypertension (PAH) based on integrated bioinformatics analysis. The Gene Expression Omnibus (GEO) database was used to download three mRNA expression profiles comprising 91 PAH lung specimens and 49 normal lung specimens. Three mRNA expression datasets were combined, and differentially expressed genes (DEGs) were obtained.
View Article and Find Full Text PDFObjective: The NoSAS score is a new tool widely used in recent years to screen for obstructive sleep apnea. A number of studies have shown that the NoSAS score is more accurate than previous tools, such as the Berlin, STOP-Bang, and STOP questionnaires. Therefore, this meta-analysis assessed the diagnostic value of the NoSAS score for sleep apnea syndrome in comparison to polysomnography.
View Article and Find Full Text PDFBackground: Pulmonary arterial hypertension (PAH) is a disease or pathophysiological syndrome which has a low survival rate with abnormally elevated pulmonary artery pressure caused by known or unknown reasons. In addition, the pathogenesis of PAH is not fully understood. Therefore, it has become an urgent matter to search for clinical molecular markers of PAH, study the pathogenesis of PAH, and contribute to the development of new science-based PAH diagnosis and targeted treatment methods.
View Article and Find Full Text PDFBackground: Lung cancer is an intractable disease and the second leading cause of cancer-related deaths and morbidity in the world. This study conducted a bioinformatics analysis to identify critical genes associated with poor prognosis in non-small cell lung cancer (NSCLC).
Methods: We downloaded three datasets (GSE33532, GSE27262, and GSE18842) from the gene expression omnibus (GEO), and used the GEO2R online tools to identify the differentially expressed genes (DEGs).
Non-commercial forests represent important habitats for the maintenance of biodiversity and ecosystem function in China, yet no studies have explored the patterns and determinants of plant biodiversity in these human dominated landscapes. Here we test the influence of (1) forest type (pine, mixed, and broad-leaved), (2) disturbance history, and (3) environmental factors, on tree species richness and composition in 600 study plots in eastern China. In total, we found 143 species in 53 families of woody plants, with a number of species rare and endemic in the study region.
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