Dual-mode detection of dopamine based on 0D/2D/2D CuInS/ZnS quantum dot-black phosphorous nanosheet-TiO nanosheet nanocomposites.

In this work, we designed new dual-mode "turn-on" electrochemical (EC) and photoelectrochemical (PEC) sensors for the detection of dopamine (DA) based on 0D/2D/2D CuInS/ZnS quantum dot (QD)-black phosphorous nanosheet (BPNS)-TiO nanosheet (TiONS) nanocomposites. QDs can not only improve the photocurrent of the developed PEC sensors, but also provide the electrochemical signal in the EC detection. BPNSs as p-type semiconductor with high conductive properties work as electron acceptors and are utilized to improve the sensitivity of the DA PEC and EC sensors.

Controllable Synthesis and Biological Application of Schiff Bases from d-Glucosamine and Terephthalaldehyde.

Theoretically, the two aldehydes of terephthalaldehyde (TPA) are equivalent, so the single or double Schiff base from TPA and d-glucosamine (Glc) may be formed at the same time. However, it is preferred to produce separately a single Schiff base ( ) or double Schiff base ( ) for different synthesis systems of anhydrous methanol or water-methanol. We calculated the Δ of the formation of compounds and by density functional theory (DFT).

A tyrosinase-induced fluorescence immunoassay for detection of tau protein using dopamine-functionalized CuInS/ZnS quantum dots.

Rapid, highly sensitive detection of tau protein and other neurodegenerative biomarkers remains a significant hurdle for diagnostic tests for Alzheimer's disease. In this work, we developed a novel tyrosinase (TYR)-induced tau aptamer-tau-tau antibody (anti-tau) sandwich fluorescence immunoassay to detect tau protein that used dopamine (DA)-functionalized CuInS/ZnS quantum dots as the fluorophore. CuInS/ZnS core/shell quantum dots with high luminescence, low toxicity, and excellent biocompatibility were successfully fabricated and decorated with DA through amide conjugation.

Development of CdSe⁻ZnO Flower-Rod Core-Shell Structure Based Photoelectrochemical Biosensor for Detection of Norovirous RNA.

In this work, the CdSe⁻ZnO flower-rod core-shell structure (CSZFRs) was prepared by ion-exchange method. The surface of CSZFRs was modified by 3-mercaptopropionic acid (MPA), and then the DNA probe was immobilized on the surface via chemical bond between -NH₂ of DNA probe and -COOH of MPA. Finally, the target norovirous (NV) RNA was combined with the probe according to the principle of complementary base pairing, resulting in a decrease of the photocurrent.