Prognostic model construction and target identification of Si-Wu-Tang against breast cancer.

The targets and mechanisms of Si-Wu-Tang (SWT) against (Breast cancer) BRCA were identified and a survival model and nomogram was construted by network pharmacology, bioinformatic analysis and experiments. A total of 72 anti-breast cancer SWT targets were selected, among which eleven genes () were used to construct a novel prognostic model of breast cancer. The anti-breast cancer activity of SWT was related to the modulation of the receptor tyrosine kinases signaling pathways.