Publications by authors named "Jinping Guo"

Introduction: Magnesium (Mg) is a crucial macronutrient for plants. Understanding the molecular responses of plants to different levels of Mg supply is important for improving cultivation practices and breeding new varieties with efficient Mg utilization.

Methods: In this study, we conducted a comprehensive transcriptome analysis on tobacco ( L.

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  • * Researchers identified 59 CBF gene family members in five yellowhorn cultivars, with 8 core genes common across them, showing structural diversity and evolutionary adaptations.
  • * A specific gene was found to significantly improve cold tolerance in transgenic yellowhorn plants, enhancing antioxidant activity and reducing damage compared to wild-type plants under low-temperature stress.
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Superoxide dismutase (SOD) is widely present in plants and plays a crucial role in defending against oxidative stress and preventing tissue damage. This study discovered that the gene in 84K poplar ( × ) exhibits a distinct capacity to be induced in response to salt stress. To delve into the pivotal role of in conferring salt tolerance, the entire fragment was successfully cloned from 84K poplar and the potential function of was explored using bioinformatics and subcellular localization.

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Introduction: Rhizosphere effects (REs) have recently been identified as important regulators of root and microbial nutrient acquisition and are positively involved in nutrient cycling of belowground carbon (C), nitrogen (N), and phosphorus (P). Nutrient conditions of the fine roots and soil N are likely to influence REs. Still, it is unclear how REs of soil nutrients themselves variably impact the supply of nutrients to plants in terms of the responses to soil N due to succession.

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Background: Boron (B) is an essential micronutrient for plants. Inappropriate B supply detrimentally affects the productivity of numerous crops. Understanding of the molecular responses of plants to different B supply levels would be of significance in crop improvement and cultivation practices to deal with the problem.

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  • Genetic variations in important pharmacogenes can affect how individuals respond to drug therapy, and this study focused on the Yi population to uncover new pharmacogenomic data.
  • Researchers assessed 54 VIP genetic variants in 200 Yi individuals and found significant differences in genotype frequencies for 4 specific SNPs when compared to 26 other populations.
  • These unique genetic differences may influence the effectiveness and potential side effects of certain medications like warfarin and cisplatin for the Yi population, aiding in more personalized treatment approaches.
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The gradual evolution of pharmacogenomics has shed light on the genetic basis for inter-individual drug response variations across diverse populations. This study aimed to identify pharmacogenomic variants that differ in Zhuang population compared with other populations and investigate their potential clinical relevance in gene-drug and genotypic-phenotypic associations. A total of 48 variants from 24 genes were genotyped in 200 Zhuang subjects using the Agena MassARRAY platform.

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Introduction: Phosphorus (P), which plays a vital role in plant growth, is continually added to soil to maximize biomass production, leading to excessive P accumulation and water eutrophication.

Results: In this study, a pot experiment using a subtropical tobacco-growing soil fertilized with four P levels-no P, low P, medium P, and high P-was conducted and rhizosphere and bulk soils were analyzed.

Results: P addition significantly increased tobacco biomass production (except under low P input) and total soil P and available P content (<0.

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  • Pharmacogenomics studies how genetic differences influence drug metabolism and reactions, aiming to understand these variations in the Jingpo population.
  • The research used the Agena MassARRAY Assay to analyze 57 genetic variants in 159 Jingpo individuals, comparing their data to 26 other populations.
  • Key findings included identifying six significant genetic loci associated with drug metabolism and toxicity, which could impact treatment efficacy and safety for Jingpo individuals.
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  • The study investigated how variations in the CYP2B6 gene (specifically SNPs) relate to the risk of lung cancer in a Chinese population.
  • Researchers analyzed 1,012 participants (507 lung cancer cases and 505 controls) using genetic testing and statistical methods to determine the association.
  • The findings revealed specific SNPs that increase or decrease lung cancer risk, highlighting the importance of these genetic variations in understanding susceptibility to the disease.
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Background: Osteonecrosis of the femoral head (ONFH) is a disease with a high disability rate, and genetic factors are closely related to its pathogenesis. This study aimed to investigate the possible correlation between ESR1 and APOE gene polymorphisms and the risk of ONFH.

Methods: In this case-control study, the potential association between three genetic variants (rs2982573 C < T, rs10872678 C < T, and rs9322332 A < C) of the ESR1 gene and two genetic variants (rs7259620 A < G and rs769446 C < T) of the APOE gene with the risk of ONFH was investigated.

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The aim of this study was to discover new biomarkers to detect breast cancer (BC), which is an aggressive cancer with a high mortality rate. In this study, bioinformatic analyses (differential analysis, weighted gene co-expression network analysis, and machine learning) were performed to identify potential candidate genes for BC to study their molecular mechanisms. Furthermore, Quantitative Real-time PCR and immunohistochemistry assays were used to examine the protein and mRNA expression levels of a particular candidate gene ().

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The integration of metasurfaces and optical waveguides is gradually attracting the attention of researchers because it allows for more efficient manipulation and guidance of light. However, most of the existing studies focus on passive devices, which lack dynamic modulation. This work utilizes the meta-waveguides with liquid crystal(LC) to modulate the on-chip spectrum, which is the first experimentally verified, to the authors' knowledge.

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Lipoxygenase (LOX) gene plays an essential role in plant growth, development, and stress response. 15 LOX genes were identified, which were unevenly distributed on chromosomes and divided into three subclasses in this study. In promoter region analysis, many cis-elements were identified in growth and development, abiotic stress response, hormonal response, and light response.

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Zinc (Zn) is an essential micronutrient for plants. Adequate regulation of Zn uptake, transport and distribution, and adaptation to Zn-deficiency stress or Zn-excess toxicity are crucial for plant growth and development. However, little has been done to understand the molecular responses of plants toward different Zn supply levels.

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Background: Leaf nutrient resorption is a key strategy in plant conservation that minimizes nutrient loss and enhances productivity. However, the differences of the nutrient resorption among garden tree species in urban ecosystems were not clearly understood, especially the differences of nitrogen resorption efficiency (NRE) and phosphorous resorption efficiency (PRE) between evergreen and deciduous trees.

Methods: We selected 40 most generally used garden tree specie belonged two life forms (evergreen and deciduous) and investigated the nitrogen (N) and phosphorus (P) concentrations in green and senesced leaves and soil nutrient concentrations of nine samples trees for each species.

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  • The study examined how Rosa roxburghii affects insulin resistance and regulates key signaling pathways in obese rats by comparing several treatment groups over a period of 20 weeks.
  • Five groups of male SD rats were divided into normal control, model, positive control, low-dose, and high-dose Rosa roxburghii, with only the normal control group on a normal diet.
  • Results showed that the model group had increased body weight and insulin resistance markers, while Rosa roxburghii treatments significantly reduced these markers and improved the signaling proteins involved in glucose regulation.
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Yellow horn grows in northern China and has a high tolerance to drought and poor soil. Improving photosynthetic efficiency and increasing plant growth and yield under drought conditions have become important research content for researchers worldwide. Our study goal is to provide comprehensive information on photosynthesis and some candidate genes breeding of yellow horn under drought stress.

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Background: Glioma is one of the common primary intracranial tumors, which is heterogeneous among individuals with a low cure rate. Our study aimed to investigate the association between single nucleotide polymorphisms (SNPs) of the OR51E1 gene and glioma susceptibility in the Chinese Han population.

Methods: A total of six SNPs on OR51E1 in 1,026 subjects (526 cases and 500 controls) were genotyped by MassARRAY iPLEX GOLD assay.

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  • Yellowhorn is a hardy deciduous tree native to Northern and Central China, valued for its ornamental use and edible seeds rich in oil and fatty acids.
  • A high-quality genome assembly of yellowhorn revealed significant gene expansions related to photosynthesis and root development, which may enhance the tree's adaptability to harsh environments.
  • The research identified a gene associated with seed oil content variation, aiding in understanding yellowhorn's genetic improvement for oil production.
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  • - The research focuses on the pharmacogenomics of the Hui population, identifying significant genetic variants that affect drug metabolism and treatment effectiveness.
  • - A total of 53 VIP variants across 26 genes were genotyped in 200 Hui individuals, revealing notable differences in genetic frequencies when compared to 26 other populations.
  • - Key variants, such as those in PTGS2, NAT2, ACE, and CYP2D6, were found to potentially impact responses to various medications, providing a basis for personalized treatments in the Hui population.
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How to build a satisfactory indoor environment has become increasingly important. In this paper, the synthesis and improvement of the most widely used polyester materials in China were carried out based on two different preparation methods, and the structures and filtration performances were tested and analyzed. The results showed that a carbon black coating was wrapped on the surfaces of the new synthetic polyester filter fibers.

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The AP2/ERF gene family involves numerous plant processes, including growth, development, metabolism, and various plant stress responses. However, several studies have been conducted on the AP2/ERF gene family in yellow horn, a new type of oil woody crop and an essential oil crop in China. According to sequence alignment and phylogenetic analyses, one hundred and forty-five AP2/ERF genes were detected from the yellow horn genome.

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In recent years, the incidence and mortality of myocardial infarction (MI) have been increasing throughout the world, threatening public health. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), play critical roles in the progression of MI. The present study aimed to investigate the role of lncRNA AK006774 in the progression of myocardial infarction and find out novel therapeutic or diagnostic target of myocardial infarction.

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Yellow horn (Xanthoceras sorbifolia) is an oil-rich woody plant cultivated for bio-energy production in China. Soil saline-alkalization is a prominent agricultural-related environmental problem limiting plant growth and productivity. In this study, we performed comparative physiological and transcriptomic analyses to examine the mechanisms of X.

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