Publications by authors named "Jinny Parkd"
Article Synopsis
- PPARγ and retinoic acid receptors (RARs) are being studied for their potential in chemotherapy for leukemia by influencing the tumor suppressor PTEN.
- Research showed that both PPARγ and RAR ligands can increase PTEN levels, leading to growth arrest in leukemia cells at the G1 phase of the cell cycle.
- The combination of these two compounds not only enhanced PTEN expression but also significantly reduced the growth rates of HL-60 leukemia cells, indicating a synergistic effect on cancer cell proliferation.
