Zearalenone (ZEN) is a secondary metabolite produced by various Fusarium species. Its widespread contamination has raised deep concern globally. Also, ZEN is reproductively toxic, hepatotoxic and carcinogenic.
View Article and Find Full Text PDFThis study aims to investigate the effect and mechanism of Fuyu Decoction(FYD) in the treatment of myocardial fibrosis in the rat model of heart failure(HF). Sixty Wistar rats were randomized into a modeling group(n=50) and a sham group(n=10). A post-myocardial infarction HF model was established by ligating the left anterior descending coronary artery in rats.
View Article and Find Full Text PDFZhongguo Zhong Xi Yi Jie He Za Zhi
September 2015
Objective: To explore targets of Chinese herbal medicine at cellular and molecular leve1s through an experimental study on Yinxingye Capsule (YC) intervening vascular endothelial cell apoptoeis of hyperhornocysteinemia (HHcy) rats.
Methods: The HHcy model was prepared in male Wistar rats. Totally 42 rats were randomly divided into 4 groups, i.