Identification of serum metabolites associated with polybrominated diphenyl ethers (PBDEs) exposure in papillary thyroid carcinoma: a case-control study.

As the most common endocrine cancer, thyroid cancer (TC) has sharply increased globally over the past three decades. The growing incidence of TC might be counted by genetics, radiation, iodine, autoimmune disease, and exposure to environmental endocrine-disrupting chemicals (EDCs). Polybrominated diphenyl ethers (PBDEs), being typical EDCs, have been widely utilized in plastics, electronics, furniture, and textiles as flame retardants since the 1980s, and research has indicated a significant correlation between their exposure and the risk of TC.

Characterization and distribution of polybrominated diphenyl ethers in shellfish in Shenzhen coastal waters and assessment of human health risks.

This study aims to investigate the profiles of polybrominated diphenyl ethers (PBDEs) in shellfish obtained from Shenzhen coastal waters and assess the potential health risks. We analyzed 74 shellfish samples from eight different species for PBDEs (BDE-28, -47, -99, -100, -153, -154, -183, -209). The concentrations of total PBDEs in different shellfish species ranged from 2.

Body burden and influencing factors of polychlorinated dibenzodioxins and dibenzofurans (PCDD/Fs) in male workers from a municipal waste incineration plant in China.

Emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) from municipal solid waste incinerators (MSWIs) have aroused public concern around the world. However, biomonitoring evidence regarding the influence of MSWIs on the human body burden of PCDD/Fs is scarce. The aim of this study is to investigate the human body burden levels of PCDD/Fs in MSWI workers and to further explore the potential influencing factors, including duration of occupation and dietary habits, on the PCDD/F levels.

Chest CT imaging characteristics and their evolution of 48 patients with COVID-19 in Hengyang, China.

The novel coronavirus 2019 (2019 nCoV), appeared in Wuhan in December 2019, can cause a novel coronavirus pneumonia (Corona Virus Disease 2019, COVID-19). COVID-19 is highly infectious and easy to infect people. The epidemic has gradually spread to all parts of the country.

Lipid metabolism disorders associated with dioxin exposure in a cohort of Chinese male workers revealed by a comprehensive lipidomics study.

Dioxins, environmentally stable and ubiquitous, have been found to induce metabolic changes especially in lipids and be related to multiple diseases. However, limited study is available on lipid alternations related to human exposure to dioxins. This study aims to explore the serum lipidomic characterization and to understand the underlying mechanisms of adverse health risks associated with dioxin exposure.

[Establishment the method for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans determination in human serum].

Objective: To establish the determination method for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans(PCDD/Fs) in human serum, and further to provide an operable and scientific determination protocal and basis for conducting human health risk assessment for PCDD/Fs.

Methods: The serum samples were pretreated by C18 column solid phase extraction, acid silica gel column and activated carbon column purification, separated by DB-5 MS capillary column(60 m×0. 25 mm×0.

A case-control study on the association of mineral elements exposure and thyroid tumor and goiter.

Thyroid tumor and thyroid goiter are prevalent disease around the world. In this case-control study, we investigated the association between exposure to a total of twelve mineral elements and thyroid disease as well as thyroid functions. Participants with thyroid tumor or goiter (N = 197) were matched with a healthy population (N = 197) by age (± 2 years old) and same sex.

Serum metabolic changes associated with dioxin exposure in a Chinese male cohort.

Dioxins, a group of persistent organic pollutants, have been proved to correlate with ranges of diseases by activating the aryl hydrocarbon receptor (AhR). However, previous dioxin toxicity studies primarily focused on the activation of AhR with signaling pathways at gene and protein levels. The investigation of underlying mechanisms at the metabolic level is still necessary.

Spatiotemporal variability of polybrominated diphenyl ether concentration in atmospheric fine particles in Shenzhen, China.

Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants for various products and have become ubiquitous pollutants in environmental media. However, little is known about PBDE levels in Shenzhen, a manufacturing center of electronic products. This study aimed to investigate spatiotemporal variability of PBDE concentration in atmospheric fine particles (PM) and to estimate the daily inhalation exposure doses for local residents in Shenzhen, China.

Toxaphene levels in retail food from the Pearl River Delta area of South China and an assessment of dietary intake.

Limited literature exists on toxaphene contamination in food worldwide, particularly in mainland China. In this study, three toxaphene congeners, Parlar 26 (B8-1413), Parlar 50 (B9-1679) and Parlar 62 (B9-1025), were analyzed in five different food categories from the Pearl River Delta Area in China using isotope dilution high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS), and toxaphene levels in food were reported and toxaphene dietary intake by local residents estimated. The results showed that fish contained the highest toxaphene level with a median of 12.

[Levels of polychlorinated dibenzo-p-dioxins and dibenzofurans in airborne fine particulate matter and inhalation risk assessment for local residents of Shenzhen].

Objective: To explore the levels and congener profiles of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in airborne fine particulate matter (PM25) in Shenzhen and roughly discuss its correlations between PM25 concentration and meteorological factors.

Methods: The high volume air samplers were used to collect the samples in six sampling sites in respective winter and spring phase and summer and autumn phase. Referring to the US EPA TO-9A for dioxins detection methods, the concentrations of the 17 polychlorinated dibenzo-p-dioxins and dibenzofurans in airborne fine particulate matter were determined by HRGC/HRMS.