The potential of repeated mean arterial pressure measurements for predicting early- and late-onset pre-eclampsia in twin pregnancies: Prediction model study.

Objective: To investigate the contribution of longitudinal mean arterial pressure (MAP) measurement during the first, second, and third trimesters of twin pregnancies to the prediction of pre-eclampsia.

Methods: A retrospective cohort study was conducted on women with twin pregnancies. Historical data between 2019 and 2021 were analyzed, including maternal characteristics and mean artery pressure measurements were obtained at 11-13, 22-24, and 28-33 weeks of gestation.

Treatment failure is a key factor in the development of Helicobacter pylori resistance.

Background: Helicobacter pylori eradication failure influences its antibiotic resistance.

Aims: This study aimed to evaluate the effect of previous treatment failures on it, including the changes in the antibiotic resistance rates, minimal inhibitory concentration (MIC) distributions, and resistance patterns.

Materials And Methods: This single-center retrospective study included 860 primary isolates and 247 secondary isolates.

Macrophage Tim-3 maintains intestinal homeostasis in DSS-induced colitis by suppressing neutrophil necroptosis.

T-cell immunoglobulin domain and mucin domain-3 (Tim-3) is a versatile immunomodulator that protects against intestinal inflammation. Necroptosis is a type of cell death that regulates intestinal homeostasis and inflammation. The mechanism(s) underlying the protective role of macrophage Tim-3 in intestinal inflammation is unclear; thus, we investigated whether specific Tim-3 knockdown in macrophages drives intestinal inflammation via necroptosis.

Impact of Helicobacter pylori colonization density and depth on gastritis severity.

Background And Objectives: Helicobacter pylori (H. pylori) infection is the most common etiology of chronic gastric. H.

Preparation of tough and stiff ionogels phase separation.

Ionogels have the advantages of thermal stability, non-volatility, ionic conductivity and environmental friendliness, and they can be used in the field of flexible electronics and soft robotics. However, their poor mechanical strength and complex preparation methods limit their practical application. Herein, we propose a simple strategy to improve the performance of ionogels by adjusting their phase separation behavior.

Design and simulation of a cross-regional collaborative recycling system for secondary resources: A case of lead-acid batteries.

In emerging economies, a significant amount of secondary resources are recycled by the informal sector, which can seriously harm the environment. However, some previous studies of industry management policy design ignored geographical factors. This paper introduces Geographic Information Systems into an agent-based cross-regional recycling model, and employs lead-acid batteries as an example.

Helicobacter pylori infection reduces the efficacy of cancer immunotherapy: A systematic review and meta-analysis.

Background: Cancer immunotherapy has shown promising results in several tumors, but its efficacy is influenced by the immune state of the body. Helicobacter pylori (H. pylori) infection can modulate the immune function of the body through various pathways, ultimately affecting the effectiveness of cancer immunotherapy.

Reinforced medication adherence improves Helicobacter pylori eradication rate in developing countries: A systematic review and meta-analysis of randomized controlled trials.

Background: The eradication rate of Helicobacter pylori (H. pylori) remains variable for the same eradication regime even in the identical region, especially in developing countries. Herein, we conducted a systematic review to assess the effect of reinforced medication adherence on H.

Green illusions in self-reporting? Reassessing the intention-behavior gap in waste recycling behaviors.

Improving residents' waste recycling behavior is crucial for enhancing resource efficiency and reducing carbon emissions. Previous questionnaire-based studies have reported that individuals exhibit a high willingness to recycle, yet often fail to convert this intention into action. Analyzing 180,417 Internet of Things (IoT) behavior data points, we discovered that the intention-behavior gap might be larger than anticipated.

Assisted reproductive technology and neurodevelopmental outcomes in offspring: a prospective birth cohort study in East China.

Research Question: Is ART associated with adverse neurodevelopmental outcome in 12-month-old offspring compared with those conceived through natural conception?

Design: In this prospective cohort study, 488 infertile women undergoing ART and 1397 women with natural conception were recruited and followed until their offspring were 12 months old. The primary outcome was the neurodevelopment in the offspring. The association between exposure to ART and Gesell developmental scale scores was investigated using multiple linear regression models after adjusting for confounders.

Electrostatically Assisted Construction Modified MXene-IL-Based Nanofluids for Photothermal Conversion.

Solar energy, as renewable energy, has paid extensive attention for solar thermal utilization due to its unique characteristics such as rich resources, easy access, clean, and pollution-free. Among them, solar thermal utilization is the most extensive one. Nanofluid-based direct absorption solar collectors (DASCs), as an important alternative method, can further improve the solar thermal efficiency.

Iatrogenic factors of Helicobacter pylori eradication failure: lessons from the frontline.

Background: Iatrogenic factors play an important role in eradication failure, whereas it can be easily missed. Therefore, we aimed to investigate and analyze these related iatrogenic factors of eradication failure.

Methods: A total of 508 patients who experienced eradication failure were included in this study conducted from December 2019 to February 2022.

A bibliometric analysis of inflammatory bowel disease and COVID-19 researches.

Background: Patients with inflammatory bowel disease (IBD) often require immunosuppressive therapy and are hence susceptible to various opportunistic viral and bacterial infections. In this regard, many studies on IBD and COVID-19 have been conducted. However, no bibliometric analysis has been performed.

Construction of a novel choline metabolism-related signature to predict prognosis, immune landscape, and chemotherapy response in colon adenocarcinoma.

Background: Colon adenocarcinoma (COAD) is a common digestive system malignancy with high mortality and poor prognosis. Accumulating evidence indicates that choline metabolism is closely related to tumorigenesis and development. However, the efficacy of choline metabolism-related signature in predicting patient prognosis, immune microenvironment and chemotherapy response has not been fully clarified.

Identification of a glycolysis- and lactate-related gene signature for predicting prognosis, immune microenvironment, and drug candidates in colon adenocarcinoma.

Colon adenocarcinoma (COAD), a malignant gastrointestinal tumor, has the characteristics of high mortality and poor prognosis. Even in the presence of oxygen, the Warburg effect, a major metabolic hallmark of almost all cancer cells, is characterized by increased glycolysis and lactate fermentation, which supports biosynthesis and provides energy to sustain tumor cell growth and proliferation. However, a thorough investigation into glycolysis- and lactate-related genes and their association with COAD prognosis, immune cell infiltration, and drug candidates is currently lacking.

An Intratumor Heterogeneity-Related Signature for Predicting Prognosis, Immune Landscape, and Chemotherapy Response in Colon Adenocarcinoma.

Background: Colon adenocarcinoma (COAD) is a frequent malignancy of the digestive system with a poor prognosis and high mortality rate worldwide. Intratumor heterogeneity (ITH) is associated with tumor progression, poor prognosis, immunosuppression, and therapy resistance. However, the relationship between ITH and prognosis, the immune microenvironment, and the chemotherapy response in COAD patients remains unknown, and this knowledge is urgently needed.

Core-Shell ZIF67@ZIF8 Modified with Phytic Acid as an Effective Flame Retardant for Improving the Fire Safety of Epoxy Resins.

Despite many important industrial applications, epoxy resin (EP) suffers from high flammability and toxicity emission, extremely hampering their applications. To circumvent the problem, core-shell structured ZIF67@ZIF8 is successfully synthesized and further functionalized with phytic acid (PA) to obtain PA-ZIF67@ZIF8 hybrids. Then, it is used as an efficient flame retardant to reduce the fire risk of EP.

The Interferon Gamma-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Colon Adenocarcinoma.

Colon adenocarcinoma (COAD) is one of the most common clinically malignant tumours of the digestive system, with high incidence and mortality and poor prognosis. Interferon-gamma (IFN-γ) and long noncoding RNAs (lncRNAs) have prognostic values and were closely associated with immune microenvironment in COAD. Thus, identifying IFN-γ-related lncRNAs may be valuable in predicting the survival of patients with COAD.

No significant relationship exists between tumor size and prognosis in distant metastatic hepatocellular carcinoma: a propensity score matching analysis based on SEER database.

Background: Previous studies have shown that tumor size has an impact on the prognosis of hepatocellular carcinoma (HCC). Whether tumor size is related to the prognosis of distant metastatic HCC is unclear. The purpose of this study was to investigate the effect of tumor size on the prognosis of distant metastatic HCC.

Copy Number Analyses Identified a Novel Gene: Related to Lipid Metabolism in the Pathogenesis of Preeclampsia.

Background: Preeclampsia is a heterogeneous and complex disease with its pathogenesis mechanism not fully elucidated. A certain subset of patients with preeclampsia exhibit disturbances in lipid metabolism before clinical symptoms. Moreover, there is a tendency for preeclampsia to run in families.

An infinite life cycle assessment model to re-evaluate resource efficiency and environmental impacts of circular economy systems.

Challenges exist in life cycle assessment (LCA) to evaluate resource efficiency and environmental impacts of circular economy systems. Rules attributing recycling benefits/burdens are inconsistent, causing system boundary ambiguity. Besides, LCAs covering one or several life cycles fail to capture the complete resource path, which leads to unfair assessment results for the primary life cycle.

Risk factors for urinary tract infection in kidney transplantation from brain death donor and its role in graft function.

Objectives: Urinary tract infection (UTI) is the most common infection complication after kidney transplantation, and the reports of the incidence vary greatly among different centers. This study aims to explore the risk factors for UTI after kidney transplantation with the donation from brain death (DBD) and the impact on graft function, thus to provide theoretical basis for comprehensive prevention and treatment of UTI after kidney transplantation.

Methods: The clinical and laboratory data of DBD kidney transplantation from January 2017 to December 2018 in Xiangya Hospital, Central South University were collected and retrospectively analyzed.

Injectable, Intrinsically Antibacterial Conductive Hydrogels with Self-Healing and pH Stimulus Responsiveness for Epidermal Sensors and Wound Healing.

Torealize intelligent and personalized medicine, it is a huge challenge to develop a hydrogel dressing that can be used as a sensor to monitor human health in real-time while promoting wound healing. Herein, an injectable, self-healing, and conductive chitosan-based (CPT) hydrogel with pH responsiveness and intrinsic antibacterial properties was fabricated via a Schiff base linkage and a hydrogen bond. Due to the introduction of Schiff base bonds, the injectable CPT hydrogel exhibits various excellent properties, such as pH responsiveness to sol-gel transition, self-healing properties, and broad-spectrum antibacterial properties even without additional antibacterial agents.

Biosafe, self-adhesive, recyclable, tough, and conductive hydrogels for multifunctional sensors.

As a bioelectronic material used in personalized medicine, it is necessary to integrate excellent adhesion and stretchability in hydrogels for ensuring biosafety. Herein, a high-performance multifunctional hydrogel of polyvinyl alcohol-sodium alginate-g-dopamine-silver nanowire-borax (PSAB) is reported. It can not only easily adhere to the surface of various substrates, but also exhibit excellent mechanical properties.