Publications by authors named "Jinkai Hu"
Triphenylphosphine, iodide and -chloro-arylsulfonamides could generate amidyl radicals EDA (Electron Donor-Acceptor) complexes under visible light irradiation, and this strategy enables the synthesis of valuable δ-chloro-arylsulfonamide and -arylsulfonylpyrrolidine motifs in moderate yields. This blue LED-induced method utilizes more readily available reagents, providing advantages in terms of cost efficiency, broad substrate scope, and functional-group compatibility.
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- - The study introduces a new chemical reaction that uses visible light to create complex compounds called trihalomethylated products without needing additional catalysts or metals.
- - The reaction effectively transforms a specific compound (2-hydroxy-2-hex-5-enenitrile) into valuable products, demonstrating versatility by also converting a different compound (benzo[]thiazol-2-yl)-pent-4-enol) into trihalo-hexanone.
- - This process operates under mild conditions, can handle various functional groups, and serves as a novel method for adding multiple functional groups to unactivated olefins.
We report the visible-light-induced PhP/LiI-promoted intermolecular cascade trifluoromethyl radical addition/5--dig cyclization/iodination of 1,6-enynes with Togni's reagent using LiI as the iodine source without the need of the transition metal, oxidant, and base. This reaction promises to be a useful method for the preparation of trifluoromethyl-substituted and vinyl C-I bond-containing pyrrolidines and benzofuran products with good regioselectivity and functional-group tolerance under ambient conditions.
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