Synopsis of recent research by authors named "Jinjin Bai"
- Jinjin Bai's recent research primarily focuses on viral infections, specifically the mechanisms by which the hepatitis B virus affects immune signaling and the implications for chronic hepatitis B patients, highlighting the role of Hepatitis B surface antigen (HBsAg) in impairing TLR4 signaling.
- Investigations into hepatocellular carcinoma (HCC) reveal that microRNA-612 can enhance ferroptosis in cancer cells, indicating a link between ferroptosis resistance and HCC metastasis, which may inform therapeutic strategies for managing HCC.
- Additionally, Bai's studies explore advanced immunotherapies, such as neoantigen-targeted TCR-engineered T cell therapies and innovative CAR-T cell designs targeting glypican-3 in HCC, suggesting potential improvements in immune microenvironment reconstitution and cancer treatment efficacy.