Publications by authors named "Jinhun Park"

Background: Musculoskeletal symptoms, such as neck pain and low back pain (LBP) are common after a traffic accident (TA). While motion-style acupuncture treatment (MSAT) is effective in relieving pain, MSAT using traction (T-MSAT) has rarely been studied, and evidence for its efficacy and safety is lacking. To address this gap, this study aimed to assess the effectiveness and safety of T-MSAT for pain and functional disturbances in patients with acute LBP caused by a TA.

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Purpose: This study is a retrospective, cross-sectional study aiming to present basic data on the treatment modalities and cost of care for primary dysmenorrhea (PD) by analyzing healthcare utilization and patient distributions using the 2010 to 2018 Health Insurance Review and Assessment Service (HIRA) data.

Patients And Methods: We used the HIRA-National Patient Sample (NPS) data to analyze medical service utilization for PD (ICD-10 code: N94.4, N94.

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Article Synopsis
  • - The study focuses on treating acute low back pain (LBP) caused by traffic accidents using a specific acupuncture therapy called motion style acupuncture therapy with traction (T-MSAT).
  • - Conducted at Jaseng Hospital in South Korea, the randomized controlled trial (RCT) will involve 100 participants, comparing T-MSAT combined with integrative Korean medicine therapy against a control group receiving only the latter.
  • - The outcomes will analyze pain relief and functional improvements using various scales, and the results can inform policymakers and healthcare providers on effective treatments for LBP post-traffic accidents.
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Article Synopsis
  • * 50 patients who had one-level corpectomy or discectomies were analyzed, with two types of plates used: Codman and Zephir, and dysphagia was assessed through follow-up interviews.
  • * Results showed that dysphagia rates (20% short-term, 14% persistent) were similar regardless of the plate type, indicating plate size does not influence the risk of developing dysphagia post-surgery.
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Study Design: A retrospective study.

Objective: To analyze the clinical outcomes and radiologic changes after microsurgical bilateral decompression via a unilateral approach in patients with lumbar spinal stenosis (LSS) and degenerative spondylolisthesis (DS).

Summary Of Background Data: Satisfactory short-term results have been observed after minimally invasive decompressive procedures, but intermediate-term and long-term outcomes have not been assessed.

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A series of 18 new imidazo[2,1-b]thiazole derivatives was synthesized. Their in vitro antiproliferative activities against A375P human melanoma cell line and NCI-60 cell line panel were tested. Compounds 15, 16, 18, 22, 26-28, and 31 showed superior potency against A375P to sorafenib.

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Article Synopsis
  • A study was conducted on new amides and esters prodrugs of olmesartan to assess their effectiveness.
  • The ester derivative IIa was found to quickly convert into olmesartan in rat plasma, doing so within just 30 minutes.
  • Pharmacokinetic analysis suggests that IIa could serve as a promising prodrug for olmesartan, potentially improving its therapeutic use.
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Synthesis of a new series of diarylureas and amides having pyrrolo[2,3-d]pyrimidine scaffold is described. Their in vitro antiproliferative activities against A375 human melanoma cell line and HS 27 fibroblast cell line were tested and the effect of substituents on pyrrolo[2,3-d]pyrimidine was investigated. The newly synthesized compounds, except N-acetyl derivatives (Id, Ie, and Im), generally showed superior or similar activity against A375 to Sorafenib.

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