Near-Infrared Light Photodynamic Therapy with PEI-Capped Up-Conversion Nanoparticles and Chlorin e6 Induces Apoptosis of Oral Cancer Cells.

Oral squamous cell carcinoma (OSCC) is a common malignancy in the oral cavity. Photodynamic therapy (PDT) is a new alternative for the treatment of diseases using photosensitizers (PS) and light. In this study, we used a photosensitizer complex (Ce6-MnNPs-Chlorin e6 combined with up-conversion nanoparticles NaYF:Yb/Er/Mn) to investigate the therapeutic effectiveness of this treatment against oral cancer cells.

OsEXPA7 Encoding an Expansin Affects Grain Size and Quality Traits in Rice (Oryza sativa L.).

Background: Yield and quality are the two most important traits in crop breeding. Exploring the regulatory mechanisms that affect both yield and quality traits is of great significance for understanding the molecular genetic networks controlling these key crop attributes. Expansins are cell wall loosening proteins that play important roles in regulating rice grain size.

Post-transcriptional regulation of grain weight and shape by the RBP-A-J-K complex in rice.

RNA-binding proteins (RBPs) are components of the post-transcriptional regulatory system, but their regulatory effects on complex traits remain unknown. Using an integrated strategy involving map-based cloning, functional characterizations, and transcriptomic and population genomic analyses, we revealed that RBP-K (LOC_Os08g23120), RBP-A (LOC_Os11g41890), and RBP-J (LOC_Os10g33230) encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related traits. Examinations of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function normally.

MG-SIN: Multigraph Sparse Interaction Network for Multitask Stance Detection.

Stance detection on social media aims to identify if an individual is in support of or against a specific target. Most existing stance detection approaches primarily rely on modeling the contextual semantic information in sentences and neglect to explore the pragmatics dependency information of words, thus degrading performance. Although several single-task learning methods have been proposed to capture richer semantic representation information, they still suffer from semantic sparsity problems caused by short texts on social media.

RNA-Seq Transcriptome Analysis and Evolution of , a Gene Involved in Enhanced Spikelet Number per Panicle in Rice.

Spikelet number per panicle (SNP) is one of the most important yield components in rice. Rice (), a gene involved in improved SNP and yield, has been cloned from an accession of Dongxiang wild rice. However, the mechanism of increasing rice SNP is poorly understood.

Changes in oral pathology teaching methods during the COVID-19 pandemic and the impact on student performance (oral pathology teaching changes during the COVID-19 pandemic).

Abstract Background/purpose: Coronavirus disease 2019 (COVID-19) has influenced the dental education in Osaka Dental University. The purpose of this study was to summarize the impact of COVID-19 on student performance and the current more appropriate teaching methods by comparing the changes in various oral pathology exam results before and after COVID-19.

Materials And Methods: The experimental and control groups consisted of second year students in the department of dentistry at our university for the years 2019 (136 people) and 2020 (125 people).

The identification and characterization of a plant height and grain length related gene in rice.

Plant height and grain size are important agronomic traits affecting rice yield. Various plant hormones participate in the regulation of plant height and grain size in rice. However, how these hormones cooperate to regulate plant height and grain size is poorly understood.

Auxin signaling module OsSK41-OsIAA10-OsARF regulates grain yield traits in rice.

Auxin is an important phytohormone in plants, and auxin signaling pathways in rice play key roles in regulating its growth, development, and productivity. To investigate how rice grain yield traits are regulated by auxin signaling pathways and to facilitate their application in rice improvement, we validated the functional relationships among regulatory genes such as OsIAA10, OsSK41, and OsARF21 that are involved in one of the auxin (OsIAA10) signaling pathways. We assessed the phenotypic effects of these genes on several grain yield traits across two environments using knockout and/or overexpression transgenic lines.

CkREV regulates xylem vessel development in in response to drought.

Drought stress poses severe threat to the development and even the survival status of plants. Plants utilize various methods responding to drought, among which the forming of more well-developed xylem in leaf vein in woody plants deserves our attention. Herein, we report a transcription factor CkREV from HD-ZIP III family in , which possesses significant functions in drought response by regulating xylem vessel development in leaf vein.

CkREV Enhances the Drought Resistance of through Regulating the Expression of Auxin Synthetase Gene .

As a common abiotic stress, drought severely impairs the growth, development, and even survival of plants. Here we report a transcription factor, REVOLUTA(CkREV), which can bidirectionally regulate the expression of the critical enzyme gene in auxin synthesis according to external environment changes, so as to control the biosynthesis of auxin and further enhance the drought resistance of plants. Quantitative analysis reveals that the expression level of both and is down-regulated after and are exposed to drought.

Antischistosomal activity of N,N'-arylurea analogs against Schistosoma japonicum.

Although the antischistosomal activities of N,N'-arylurea analogs were reported, systematic structure-activity relationships have not been conducted. In this Letter, we reported the design, synthesis and evaluation of 45 N,N'-arylurea analogs. Among these prepared compounds, 13 compounds were urea linker modified and 32 were N,N'-arylurea derivatives.