Spectral channels increase of multi-wavelength visible laser enabled by SHG-SFG hybrid processes.

Spectral evolution in nonlinear optical processes, such as second harmonic generation (SHG) and sum frequency generation (SFG), plays a crucial role in multi-wavelength generation through nonlinear frequency conversion. In this study, the enhancement of spectral performance in a multi-wavelength visible laser facilitated by SHG-SFG hybrid processes is proposed and demonstrated, for the first time to our knowledge. An output of up to eleven wavelengths can be achieved using a six-wavelength pump.

Combined PET/CT and Autoantibody Detection in Lung Nodules Diagnosis.

Objective: To assess the usefulness of combining positron emission tomography/computed tomography (PET/CT) with lung cancer autoantibody detection in identifying and managing lung nodules.

Methods: The researchers identified 160 patients with pulmonary nodules admitted to their hospital between January 2018 and January 2021. These patients were designated as the experimental group.

Establishment of a prognosis prediction model for lung squamous cell carcinoma related to PET/CT: basing on immunogenic cell death-related lncRNA.

Background: Immunogenic cell death (ICD) stimulates adaptive immunity and holds significant promise in cancer therapy. Nevertheless, the influence of ICD-associated long non-coding RNAs (lncRNAs) on the prognosis of patients with lung squamous cell carcinoma (LUSC) remains unexplored.

Methods: We employed data from the The Cancer Genome Atlas (TCGA)database to identify ICD-related lncRNAs associated with the prognosis of LUSC using univariate Cox regression analysis.

Potential application of a green fiber laser in laser display systems.

This study explores the application of optical fiber lasers in display systems by integrating a 3-doped green all-fiber laser into a laser projection display system. As a control group to compare the results, a 520 nm semiconductor green laser diode module was integrated, similar to the experimental group. The color gamut and speckle performances were studied and compared.

All-fiber cyan laser at 491.5 nm.

We report, for the first time to our knowledge, a compact continuous-wave all-fiber cyan laser. The all-fiber cavity consists of a 443-nm fiber-pigtail laser diode as pump source, a 4.5-cm single-clad Pr-doped fluoride fiber, and two custom-built dielectric-coated fiber-pigtail mirrors in the visible spectral region.

Efficacy of Camrelizumab in Advanced Non-Small-Cell Lung Cancer and Prognostic Analysis of Different PET/CT Features.

Objective: To evaluate the efficacy of the PD-1 inhibitor camrelizumab plus chemotherapy in the first-line treatment of advanced non-small-cell lung cancer (NSCLC) and the prognostic differences of patients with different PET/CT features.

Methods: Between December 2018 and October 2020, 100 patients with NSCLC assessed for eligibility treated in our institution were recruited and randomly assigned (1 : 1) to receive either the TC regimen chemotherapy (control group) or the TC regimen chemotherapy plus camrelizumab (study group). The primary endpoints were clinical efficacy, progression-free survival (PFS), and overall survival (OS).

Towards visible-wavelength passively mode-locked lasers in all-fibre format.

Mode-locked fibre lasers (MLFLs) are fundamental building blocks of many photonic systems used in industrial, scientific and biomedical applications. To date, 1-2 μm MLFLs have been well developed; however, passively mode-locked fibre lasers in the visible region (380-760 nm) have never been reported. Here, we address this challenge by demonstrating an all-fibre visible-wavelength passively mode-locked picosecond laser at 635 nm.

High-efficiency, yellow-light Dy-doped fiber laser with wavelength tuning from 568.7 to 581.9 nm.

We report, to the best of our knowledge, the first demonstration of a wavelength-tunable and highly efficient Dy-doped fiber laser operating in the yellow spectral region. A 2-m-long Dy:ZBLAN fiber pumped by a 447-nm GaN laser diode provides a strong down-conversion gain around 575 nm. A fiber end-facet mirror and a visible reflective grating in the Littrow configuration construct the resonant cavity and introduce the wavelength tunability.

Green/red pulsed vortex-beam oscillations in all-fiber lasers with visible-resonance gold nanorods.

Optical vortex beams are of tremendous interest in diverse applications for optical tweezers, high-resolution imaging, quantum information and optical communications. So far, these vortex laser sources largely rely on extra-cavity mode conversion by bulk optical elements (e.g.

MiR-30a Decreases Multidrug Resistance (MDR) of Gastric Cancer Cells.

BACKGROUND The effectiveness of chemotherapy for gastric cancer is largely limited by either intrinsic or acquired drug resistance. In this study, we aimed to explore the association between miR-30a dysregulation and multidrug resistance (MDR) in gastric cancer cells. MATERIAL AND METHODS We recruited 20 patients with advanced gastric cancer.