A novel nomogram to predict hemorrhagic transformation in ischemic stroke patients after intravenous thrombolysis.

Background: Hemorrhagic transformation (HT) is the most serious complication of ischemic stroke patients after intravenous thrombolysis and leads to a poor clinical prognosis. This study aimed to determine the independent predictors associated with HT in stroke patients with intravenous thrombolysis and to establish and validate a nomogram that combines with predictors to predict the probability of HT after intravenous thrombolysis in patients with ischemic stroke.

Method: This study enrolled ischemic stroke patients with intravenous thrombolysis from December 2016 to June 2022.