Introduction: Alzheimer's disease (AD) is a complex neurological disorder that progressively worsens. Although its exact causes are not fully understood, new research indicates that genes related to non-neuronal cells change significantly with age, playing key roles in AD's pathology.
Method: This study focuses on a protein network centered on Glial Fibrillary Acidic Protein (GFAP) and Protein Tyrosine Phosphatase Receptor Type C (PTPRC).
Introduction: When Ant Colony Optimization algorithm (ACO) is adept at identifying the shortest path, the temporary solution is uncertain during the iterative process. All temporary solutions form a solution set.
Methods: Where each solution is random.
Two-dimensional topological insulators (2D TIs) have distinct electronic properties that make them attractive for various applications, especially in spintronics. The conductive edge states in 2D TIs are protected from disorder and perturbations and are spin-polarized, which restrict current flow to a single spin orientation. In contrast, topological nodal line semimetals (TNLSM) are distinct from TIs because of the presence of a 1D ring of degeneracy formed from two bands that cross each other along a line in the Brillouin zone.
View Article and Find Full Text PDFObjective: Accurate prediction of hospital length of stay (LOS) following surgical management of oral cavity cancer (OCC) may be associated with improved patient counseling, hospital resource utilization and cost. The objective of this study was to compare the performance of statistical models, a machine learning (ML) model, and The American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) calculator in predicting LOS following surgery for OCC.
Materials And Methods: A retrospective multicenter database study was performed at two major academic head and neck cancer centers.
Objective: To examine the association between dipeptidyl peptidase-4 inhibitors and gallbladder or biliary diseases.
Design: Systematic review and pairwise and network meta-analysis.
Data Sources: PubMed, EMBASE, Web of Science, and CENTRAL from inception until 31 July 2021.
Textbook Question Answering (TQA) is the task of answering diagram and non-diagram questions given large multi-modal contexts consisting of abundant text and diagrams. Deep text understandings and effective learning of diagram semantics are important for this task due to its specificity. In this paper, we propose a Weakly Supervised learning method for TQA (WSTQ), which regards the incompletely accurate results of essential intermediate procedures for this task as supervision to develop Text Matching (TM) and Relation Detection (RD) tasks and then employs the tasks to motivate itself to learn strong text comprehension and excellent diagram semantics respectively.
View Article and Find Full Text PDFImportance: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been widely recommended for glucose control and cardiovascular risk reduction in patients with type 2 diabetes, and more recently, for weight loss. However, the associations of GLP-1 RAs with gallbladder or biliary diseases are controversial.
Objective: To evaluate the association of GLP-1 RA treatment with gallbladder and biliary diseases and to explore risk factors for these associations.
Acta Otorhinolaryngol Ital
October 2021
Objective: We determined the influence of gastro-oesophageal reflux disease (GERD) on quality of life (QOL) before and after functional-endoscopic-sinus-surgery (FESS) for chronic rhinosinusitis (CRS).
Methods: Medically-recalcitrant CRS patients were recruited prior to FESS. GERD was diagnosed endoscopically.
This study identifies participants ineligible for lung cancer screening with the greatest likelihood of future eligibility. Lung cancer risk in participants enrolled in longitudinal lung screening was assessed using the Prostate, Lung, Colorectal and Ovarian lung cancer risk calculator (PLCO) at two timepoints: baseline (T) and follow-up (T). Separate analyses were performed on four PLCO eligibility thresholds (3.
View Article and Find Full Text PDFObjective: This study aimed to systematically evaluate the association between triceps skinfold (TSF) thickness (which indicates subcutaneous fat) mid-arm muscle circumference (MAMC; which reflects muscle mass), mid-upper arm circumference (MUAC), and all-cause mortality.
Methods: A total of 17,717 adults from the China Health and Nutrition Survey (1993-2015) were included. Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality.
Despite the curative potential of allogeneic hematopoietic cell transplantation (HCT) for myelofibrosis (MF), a significant number of patients with MF do not undergo HCT. Factors influencing treatment preferences in these patients have not been well studied. This study was conducted to identify patient-, disease-, and donor-related factors influencing the decision regarding HCT in patients with MF.
View Article and Find Full Text PDFPurpose: To determine the outcomes of oral cavity squamous cell cancer (OSCC) patients treated with non-surgical approach i.e. definitive intensity-modulated radiation therapy (IMRT).
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