Publications by authors named "Jingyu Xiong"

Article Synopsis
  • Researchers aimed to develop a new minimally invasive computer-assisted workflow for placing zygomatic implants, combining static positioning with dynamic adjustments for precision.
  • The study involved 14 aging patients, with careful measurements taken to compare the planned and actual implant placements using advanced imaging techniques.
  • Results showed that the new method was accurate and effective, with all implants remaining stable over more than a year's follow-up, demonstrating its clinical utility and safety.
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Article Synopsis
  • The study investigates non-canonical splicing variants (NCSVs) and their potential role in neurodevelopmental disorders (NDDs) using a large dataset of de novo variants from patients.
  • Researchers found a significant presence of NCSVs in NDD patients compared to controls and confirmed their impact on mRNA splicing through experiments.
  • The findings suggest that NCSVs are clinically relevant, with many being novel variants, and highlight the need for further investigation into their role in the pathology of NDDs.
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B-mode ultrasonography and sonoelastography are used in the clinical diagnosis of prostate cancer (PCa). A combination of the two ultrasound (US) modalities using computer aid may be helpful for improving the diagnostic performance. A technique for computer-aided diagnosis (CAD) of PCa is presented based on multimodal US.

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Objectives: To examine the role of quantitative real-time elastography (RTE) features on differentiation between high-risk prostate cancer (PCA) and non-high-risk prostatic diseases in the initial transperineal biopsy setting.

Methods: We retrospectively included 103 patients with suspicious PCA who underwent both RTE and initial transperineal prostate biopsy. Patients were grouped into high-risk and non-high-risk categories according to the D'Amico's risk stratification.

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Chemical constituents in ethyl acetate and butanol fractions of ethanol extracts from Acorus tatarinowii were separated by column chromatography. Bufo skeletal muscle fatigue model was established to study the anti-fatigue activity of separated compounds. Five compounds were separated and identified by spectroscopic analysis as acoramone(1),cycloartenone(2),2,4,5-trimethoxyl-2'-butoxy-1,2-phenyl propandiol(3),5-hydroxymethyl furfural(4), and 5-butoxymethyl furfural(5).

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A reversed phase (RP)-HPLC method was established for simultaneous determination of chlorogenic acid, arctiin and forsythin in Yinqiao Jiedu Granules, which was a commonly used Chinese herbal medical preparation for treatment of rheum ailments. The determination was based on a gradient elution (A: 1% acetic acid, pH=3.0, B: methanol) on a C18 column and an automatic wavelength switching program, where 325 nm was used for chlorogenic acid and 280 nm for arctiin and forsythin, respectively.

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