Cognitive decline is an important feature of an aging population. Despite the large body of research investigating the effects of high-intensity interval training (HIIT) on cognitive performance, reports of its effectiveness are inconsistent and it is difficult to determine what factors moderate these effects. The purpose of this study was to conduct a meta-analysis of existing randomised controlled trials investigating the effects of HIIT on various domains of cognitive performance, and to further examine the intervention cycle and age-related moderating effects.
View Article and Find Full Text PDFBackground: General and abdominal obesity are prevalent, with established associations to frailty in the elderly. However, few studies have investigated these associations in patients with chronic kidney disease (CKD), yielding inconsistent results.
Methods: This cross-sectional study analysed data from the National Health and Nutrition Examination Survey (NHANES 2003-2018).
Duck Tembusu virus (DTMUV) belongs to the Flaviviridae family and mainly infects ducks. The genome of DTMUV is translated into a polyprotein, which is further cleaved into several protein by viral NS2B3 protease and host proteases. Crucially, the cleavage of the NS2A/2B precursor during this process is essential for the formation of replication complexes and viral packaging.
View Article and Find Full Text PDFCarbapenem-resistant Enterobacteriaceae (CRE) is a major pathogen that poses a serious threat to human health. Unfortunately, currently, there are no effective measures to curb its rapid development. To address this, an in-depth study on the surface-enhanced Raman spectroscopy (SERS) of 22 strains of 7 categories of CRE using a gold silver composite SERS substrate was conducted.
View Article and Find Full Text PDFAnomalous perceptual experiences in adolescents are common and may predict future psychotic disorders and other psychopathologies. However, the underlying structure and their specific relationships with bullying victimizations, a typical stressor for adolescents, remain unclear. Therefore, the current study aimed to clarify the structure of perceptual anomalies as assessed by the Cardiff Anomalous Perceptions Scale (CAPS) using exploratory graph analysis (EGA), a new factor retention method based on network psychometrics.
View Article and Find Full Text PDFPolycyclic aromatic hydrocarbon (PAH) contamination at e-waste recycling sites poses high ecological and human-health risks. Of note, PAHs in surface soils can be mobilized through colloid-facilitated transport, and may migrate into the subsurface and pollute groundwater. Here, we show that the colloids released from the soil samples at an e-waste recycling site in Tianjin, China contain high concentrations of PAHs, with total concentrations of 16 PAHs as high as 1520 ng/g dw.
View Article and Find Full Text PDFAim: Clinical heterogeneity exists in overall obesity and abdominal obesity in terms of insulin secretion and sensitivity. Further, the impact of visceral fat (VF) on the first- and second-phase insulin secretion (FPIS and SPIS) is controversial. We aim to investigate insulin secretion and sensitivity in Chinese patients with T2DM according to different BMI and VF levels.
View Article and Find Full Text PDFWe demonstrate a systematic study optimizing the properties of CoCrFeNi medium entropy alloy (MEA) thin films by tuning the deposition parameters of the pulsed direct current (DC) magnetron sputtering process. The chemical composition and microstructure of thin films were studied with energy dispersive X-ray spectroscopy (EDS), an X-ray diffractometer (XRD) and a transmission electron microscope (TEM). Abundant nanotwins and the dual face-centered cubic-hexagonal close-packed (FCC-HCP) phases were formed in some specimens.
View Article and Find Full Text PDFAim: This study aimed to explore the relationship between lower-limb muscle mass/visceral fat area and diabetic kidney disease (DKD) progression in patients with type 2 diabetes mellitus (T2DM).
Methods: A total of 879 participants with T2DM were divided into 4 groups according to the prognosis of CKD classification from Kidney Disease: Improving Global Outcomes (KDIGO). Rectus femoris cross-sectional area (RFCSA) was measured through ultrasound, and visceral fat area (VFA) was evaluated with bioelectric impedance analysis (BIA).
Aims: Visceral fat (VF) influences left ventricular (LV) structure and diastolic function in type 2 diabetes (T2DM). However, there are limited data on the association among them based on different BMI levels as well as accounting for arterial stiffness. This study investigated the association of fat distribution, arterial stiffness, left ventricular (LV) structure and diastolic function in T2DM patients.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
August 2022
Benzene is a ubiquitous pollutant and mainly accumulates in adipose tissue which has important roles in metabolic diseases. The latest studies reported that benzene exposure was associated with many metabolic disorders, while the effect of benzene exposure on adipose tissue remains unclear. We sought to investigate the effect using and experiments.
View Article and Find Full Text PDFAccumulation of polybrominated diphenyl ethers (PBDEs) in surface soils at elevated concentrations is common at e-waste recycling sites. Even though highly insoluble, migration of PBDEs into the vadose zone and groundwater is possible, due to their association with soil colloids. Here, we show that upon equilibration with artificial rainwater surface and subsurface soil samples collected at an e-waste recycling site release significant quantities of colloids, with the total concentrations of 14 PBDE congeners as high as 990 ng/g dw.
View Article and Find Full Text PDFBackground: Coronavirus Disease 2019 (COVID-19) is a global pandemic and an anxiety-provoking event. There are few studies to identify potential risk and protective factors related to anxiety during COVID-19 pandemic.
Methods: We collected information on demographic data and lifestyles by a web-based survey of 19,802 participants from 34 provinces in China during COVID-19 pandemic.
Oxygen-deficient substoichiometric titanium oxides, or "titanium suboxides," are produced incidentally from coal combustion and are environmentally abundant. Additionally, titanium suboxide nanomaterials are promising new materials with likely future environmental release. How these materials may affect contaminant fate differently than stoichiometric TiO (nano)materials is largely unknown.
View Article and Find Full Text PDFGlutaredoxins (Grxs) with Cys-Pro-Phe (Tyr)-Cys motif and a thioredoxin fold structure play an important role in the anti-oxidant system of bacteria by catalyzing a variety of thiol-disulfide exchange reactions with a 2-Cys mechanism or a 1-Cys mechanism. However, the catalytic and physiological mechanism of Corynebacterium glutamicum Mycoredoxin 1 (Mrx1) that shares a high amino acid sequence similarity to Grxs has not been fully elucidated. Here, we report that Mrx1 has a protective function against various adverse conditions, and the decrease of cell viability to various stress conditions by deletion of the Mrx1 in C.
View Article and Find Full Text PDFBackground: Corynebacterium glutamicum thrives under oxidative stress caused by the inevitably extreme environment during fermentation as it harbors antioxidative stress genes. Antioxidant genes are controlled by pathway-specific sensors that act in response to growth conditions. Although many families of oxidation-sensing regulators in C.
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